Norflex (Orphenadrine Citrate)

Orphenadrine citrate, the active ingredient in Norflex, is an anticholinergic muscle relaxant presented as an oral tablet for systemic use. It reduces skeletal muscle spasm and alleviates acute musculoskeletal pain, primarily in adult patients requiring short‑term relief.

GNH USA supplies Norflex as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The product conforms to EU regulatory standards and is manufactured under GMP conditions. Our distribution network ensures reliable access across multiple regions, and we provide comprehensive documentation and support for regulatory compliance.

Norflex (orphenadrine citrate) is used to manage conditions involving skeletal muscle spasm and associated pain.

- Muscle spasm: provides relief of involuntary muscle contraction and associated discomfort. - Acute musculoskeletal pain: reduces pain caused by strains, sprains, or injuries to muscles and soft tissues. - Post‑operative muscle spasm: helps control spasm that may occur after surgical procedures.

Common Side Effects: - Dry mouth - Drowsiness - Dizziness - Nausea

Serious or Rare Side Effects: - Tachycardia - Urinary retention - Severe allergic reaction (rash, angioedema)

Before initiating therapy, consider the following precautions: - Cardiac history: monitor for tachycardia and arrhythmias. - Hepatic function: adjust use in patients with severe liver impairment. - Glaucoma: avoid in patients with narrow‑angle glaucoma due to anticholinergic effects. - Elderly patients: increased risk of sedation, dizziness, and falls; start at the lowest effective dose. - Pregnancy: safety not established; use only if potential benefit justifies the risk. - Store at ambient temperature below 25°C: keep in the original container, protect from moisture and light.

Norflex may interact with several drug classes:

Major Interactions (Avoid): - Monoamine oxidase inhibitors (MAOIs): risk of hypertensive crisis. - Tricyclic antidepressants: additive anticholinergic effects. - Antihistamines: increased sedation and anticholinergic burden.

Moderate Interactions (Monitor Closely): - Central nervous system depressants (e.g., benzodiazepines, opioids): may enhance drowsiness. - Beta‑blockers: may mask tachycardia induced by Norflex.