Europe — EMA
Norethisterone Wockhardt Uk
GNH USA supplies Norethisterone Wockhardt Uk (Norethisterone), a progestogen for menstrual disorders, endometriosis and contraception. Request a quote supply.
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What is Norethisterone?
Norethisterone, the active ingredient in Norethisterone Wockhardt Uk, is a progestogen presented as a tablet for oral use. It is used to manage menstrual disorders, endometriosis, and as a hormonal contraceptive in women of reproductive age.
GNH USA supplies Norethisterone Wockhardt Uk as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.
What is Norethisterone used for?
Norethisterone acts on the hormonal pathways that regulate the menstrual cycle and ovulation.
Menstrual disorders: regulates irregular bleeding and reduces dysmenorrhea. Endometriosis: suppresses ectopic endometrial tissue growth and alleviates pelvic pain. Contraception: prevents ovulation and creates an unfavorable endometrial environment for implantation. Secondary amenorrhea: induces withdrawal bleeding and restores menstrual cycles.
What are the side effects of Norethisterone?
Norethisterone may cause a range of adverse reactions, most of which are mild and reversible.
Common Side Effects: - Nausea - Headache - Breast tenderness - Weight gain - Mood changes - Irregular bleeding
Serious or Rare Side Effects: - Venous thromboembolism - Severe allergic reaction (anaphylaxis) - Hepatic dysfunction - Depression or mood disorders - Visual disturbances - Severe abdominal pain
What precautions apply to Norethisterone?
Before prescribing Norethisterone, clinicians should evaluate individual risk factors and contraindications.
Pregnancy: contraindicated; avoid use during pregnancy. Breastfeeding: not recommended; assess risk versus benefit. History of thromboembolism: avoid due to increased clot risk. Liver disease: use with caution; monitor hepatic function. Smoking over 15 cigarettes/day: contraindicated in women over 35. Store at ambient temperature: keep below 25°C, protect from moisture and light.
What does Norethisterone interact with?
Norethisterone can interact with several drug classes, altering its efficacy or safety profile.
Major Interactions (Avoid): - Combined hormonal contraceptives containing estrogen: increased risk of thromboembolism. - Antifungal azoles (e.g., ketoconazole): may increase plasma levels of norethisterone. - Antiretroviral protease inhibitors: may reduce contraceptive effectiveness.
Moderate Interactions (Monitor Closely): - Rifampicin and other enzyme inducers: may lower plasma concentration. - Anticonvulsants (phenytoin, carbamazepine): may reduce efficacy. - St. John's Wort: may decrease drug levels and effectiveness.



