GNH USA

Europe — EMA

Noradrenalin Léčiva (Noradrenaline Tartrate)

GNH USA supplies Noradrenalin Léčiva (Noradrenaline Tartrate), a vasopressor for septic shock, cardiogenic shock and acute hypotension.

Noradrenaline Tartrate

Request sourcing

1
Pack/s

What is Noradrenaline Tartrate?

Noradrenaline tartrate, the active ingredient in Noradrenalin Léčiva, is a sympathomimetic presented as an injectable solution for intravenous use. It raises blood pressure in patients with acute hypotension or shock.

GNH USA supplies Noradrenalin Léčiva as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals worldwide.

What is Noradrenaline Tartrate used for?

Noradrenaline tartrate is used in the management of acute hypotensive states and shock. - Septic shock: restores systemic vascular resistance and improves blood pressure. - Cardiogenic shock: supports cardiac output by increasing heart contractility and vascular tone. - Acute hypotension during surgery: maintains hemodynamic stability under anesthesia.

What are the side effects of Noradrenaline Tartrate?

Noradrenaline tartrate may be associated with a range of adverse reactions, varying from frequent to rare.

Common Side Effects: - Tachycardia - Headache - Peripheral ischemia - Nausea - Anxiety - Arrhythmias

Serious or Rare Side Effects: - Cardiac ischemia - Severe hypertension - Tissue necrosis at infusion site - Pulmonary edema - Reflex bradycardia - Life‑threatening arrhythmias

What precautions apply to Noradrenaline Tartrate?

When using Noradrenalin Léčiva, careful monitoring and specific safety measures are essential. - Dose titration: adjust infusion rate to achieve target arterial pressure. - Cardiovascular monitoring: continuous ECG and arterial line monitoring required. - Risk of arrhythmia: observe for tachyarrhythmias and treat promptly. - Peripheral perfusion: avoid extravasation; inspect infusion site regularly. - Drug interactions: review concomitant vasoactive agents for additive effects. - Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.

What does Noradrenaline Tartrate interact with?

Noradrenalin tartrate can interact with several drug classes, necessitating vigilance.

Major Interactions (Avoid): - MAO inhibitors: may precipitate hypertensive crisis. - Tricyclic antidepressants: additive sympathomimetic activity. - β‑blockers: can blunt β1‑mediated cardiac effects.

Moderate Interactions (Monitor Closely): - Diuretics: may enhance hypotensive response. - ACE inhibitors: can cause unpredictable blood pressure changes. - Sedatives: may mask signs of excessive vasoconstriction. - Calcium channel blockers: potential for synergistic cardiovascular effects.

Frequently asked questions

What is Noradrenalin Léčiva used for?+
Noradrenalin Léčiva is an intravenous formulation of noradrenaline tartrate used to raise blood pressure in patients experiencing severe hypotension, such as those with septic shock, cardiogenic shock, or acute hypotension during surgical procedures.
How does noradrenaline tartrate work?+
The drug acts as a direct agonist at alpha‑1 and beta‑1 adrenergic receptors. Alpha‑1 stimulation causes vasoconstriction, while beta‑1 activation increases heart contractility and rate, together elevating systemic vascular resistance and cardiac output to improve arterial pressure.
What is the usual dose of Noradrenalin Léčiva?+
Dosing is individualized and must be determined by the prescribing clinician. The infusion rate is titrated to the patient’s hemodynamic response, aiming for a target mean arterial pressure while monitoring for adverse effects.
Is Noradrenalin Léčiva safe in pregnancy or breastfeeding?+
Safety data in pregnancy and lactation are limited. The drug should only be used when the potential benefit to the mother outweighs any possible risk to the fetus or infant, and only under specialist supervision.
How do I order Noradrenalin Léčiva from GNH USA?+
Submit an enquiry on the product page at gnh-usa.com, specifying the required quantity. GNH USA works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain where needed) and import documentation.
How does Noradrenalin Léčiva compare with dopamine as a vasopressor?+
Both agents raise blood pressure, but noradrenaline primarily stimulates alpha‑1 receptors, giving strong vasoconstriction with modest beta‑1 activity, whereas dopamine has dose‑dependent effects on dopaminergic, beta‑1 and alpha‑1 receptors. Noradrenaline is generally preferred for septic shock because it provides more predictable vasoconstriction with fewer tachyarrhythmias.
What are the storage and handling requirements for Noradrenalin Léčiva?+
The product should be stored refrigerated at 2‑8 °C, protected from light, and must not be frozen or shaken. Before use, inspect the solution for particulate matter or discoloration and allow it to reach room temperature if required for infusion.
How is Noradrenalin Léčiva administered?+
It is given as a continuous intravenous infusion. The solution is added to a compatible carrier fluid and delivered via a calibrated infusion pump, with the rate adjusted according to the patient’s blood pressure and clinical response.
What are the most serious risks to watch for when using Noradrenalin Léčiva?+
Serious concerns include severe hypertension, myocardial ischemia, tissue necrosis from extravasation, and life‑threatening arrhythmias. Continuous hemodynamic monitoring and careful site inspection are essential to detect these complications early.
Who should not use Noradrenalin Léčiva?+
Patients with known hypersensitivity to noradrenaline or any excipients, those with uncontrolled ventricular tachyarrhythmias, or individuals in whom excessive vasoconstriction could worsen peripheral ischemia should not receive the drug.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.
Send a sourcing enquiry for this product →

Product details

Drug
Noradrenaline Tartrate
Route
Intravenous Use
Manufacturer
Zentiva, K.S.
Origin
EU

Related products

Cronomir

Cronomir

Noradrenaline Tartrate

Laboratoire Aguettant
EU
L-Noradrenalina Braun

L-Noradrenalina Braun

Noradrenaline Tartrate

B. Braun Medical Lda.
EU
Levophed

Levophed

Noradrenaline Tartrate

Hospira Benelux
EU
Levophed

Levophed

Noradrenaline Tartrate

Hospira Benelux
EU