GNH USA

Europe — EMA

Noradrenaline (Norepinephrine) Hospira Uk (Noradrenaline Tartrate)

GNH USA supplies Noradrenaline (Norepinephrine), a vasopressor for acute hypotension, septic shock and cardiogenic shock. Request a quote for global supply.

Noradrenaline Tartrate

Request sourcing

1
Pack/s

What is Noradrenaline Tartrate?

Noradrenaline, the active ingredient in Noradrenaline (Norepinephrine) Hospira Uk, is an adrenergic agonist presented as an injection solution for intravenous use. It treats acute hypotension, septic shock, cardiogenic shock and cardiac arrest in hospitalized patients.

GNH USA supplies Noradrenaline (Norepinephrine) Hospira Uk as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals worldwide.

What is Noradrenaline Tartrate used for?

Noradrenaline acts as a potent vasopressor in critical care settings, supporting blood pressure and cardiac output.

Acute hypotension: restores vascular tone and raises systemic blood pressure. Septic shock: counteracts profound vasodilation to maintain perfusion. Cardiogenic shock: improves myocardial contractility and systemic circulation. Cardiac arrest: provides immediate circulatory support during resuscitation.

What are the side effects of Noradrenaline Tartrate?

Noradrenaline may produce a range of adverse reactions that clinicians monitor during infusion.

Common Side Effects: - Headache: mild to moderate intensity. - Tachycardia: increased heart rate due to beta‑1 stimulation. - Peripheral ischemia: reduced blood flow to extremities. - Arrhythmias: irregular heart rhythms. - Nausea: occasional gastrointestinal upset. - Anxiety: feelings of restlessness.

Serious or Rare Side Effects: - Severe hypertension: dangerously high blood pressure. - Myocardial ischemia: reduced heart muscle oxygenation. - Tissue necrosis: from extravasation at the infusion site. - Pulmonary edema: fluid accumulation in lungs. - Cardiac arrest: rare but life‑threatening event.

What precautions apply to Noradrenaline Tartrate?

Noradrenaline requires careful monitoring and specific safety measures before and during administration.

Dose titration: adjust infusion rate based on continuous blood pressure monitoring. Cardiac monitoring: observe for arrhythmias and ischemic changes. Extravasation risk: use central venous access when possible. Pregnancy and lactation: use only if benefits outweigh potential risks. Drug compatibility: verify compatibility with other IV solutions before mixing. Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.

What does Noradrenaline Tartrate interact with?

Noradrenaline can interact with several agents, altering its efficacy or safety profile.

Major Interactions (Avoid): - Beta‑blockers: may blunt the desired increase in cardiac output. - MAO inhibitors: can potentiate hypertensive effects. - Tricyclic antidepressants: increase risk of severe hypertension.

Moderate Interactions (Monitor Closely): - Vasodilators (e.g., nitroglycerin): may require higher noradrenaline doses. - Calcium channel blockers: can affect vascular response. - Diuretics: may influence intravascular volume and response.

Frequently asked questions

What is Noradrenaline (Norepinephrine) used for?+
Noradrenaline, also known as norepinephrine, is used in critical care to treat severe low blood pressure and shock states such as acute hypotension, septic shock, cardiogenic shock, and cardiac arrest. It acts quickly to raise vascular tone and improve cardiac output, helping to restore adequate organ perfusion in emergency and intensive care settings.
How does Noradrenaline work in the body?+
Noradrenaline works by directly stimulating alpha‑1 adrenergic receptors, causing blood vessels to constrict, and beta‑1 receptors, increasing heart muscle contractility. This dual action raises systemic vascular resistance and cardiac output, leading to a rapid increase in arterial blood pressure, which is essential for managing life‑threatening hypotension.
What is the usual dose of Noradrenaline?+
The dose of Noradrenaline is individualized and set by the prescribing clinician based on the patient’s condition, blood pressure response, and monitoring data. Dosage is typically adjusted in micrograms per kilogram per minute via an intravenous infusion, with continuous hemodynamic monitoring to ensure safety and efficacy.
Is Noradrenaline safe during pregnancy or breastfeeding?+
Safety data for Noradrenaline in pregnancy and lactation are limited. It should only be used when the potential benefit to the mother outweighs any possible risk to the fetus or infant. Clinicians must evaluate each case carefully and consider alternative therapies when appropriate.
How do I order Noradrenaline (Norepinephrine) from GNH USA?+
To order, submit an enquiry on the product page at gnh-usa.com, specifying the required quantity. GNH USA works with hospitals, pharmacies, and procurement teams worldwide, confirming trade or institutional credentials before providing pricing, availability, shipping details (including cold‑chain logistics if needed), and necessary import documentation.
How does Noradrenaline compare with other vasopressors?+
Noradrenaline is often preferred for its balanced alpha‑1 and beta‑1 activity, providing both vasoconstriction and modest cardiac stimulation. Compared with agents like dopamine, it has a lower risk of tachyarrhythmias, and unlike phenylephrine, it also supports heart contractility, making it a first‑line choice for many shock states.
What are the storage and handling requirements for Noradrenaline?+
Noradrenaline injection solution should be stored at 2‑8 °C, protected from light, and must not be frozen or shaken. It should be kept in its original packaging until use, and any unused portion should be discarded according to local regulations after the recommended storage period.
How is Noradrenaline administered?+
Noradrenaline is administered intravenously, usually via a central venous catheter to reduce the risk of extravasation. The drug is supplied as a sterile solution that is diluted in a compatible carrier fluid and infused using a calibrated pump, allowing precise titration of the infusion rate.
What are the most serious risks associated with Noradrenaline?+
Serious risks include severe hypertension, myocardial ischemia, tissue necrosis from extravasation, arrhythmias, and, in rare cases, cardiac arrest. Continuous hemodynamic monitoring and careful infusion site management are essential to detect and mitigate these potentially life‑threatening complications.
Who should not receive Noradrenaline?+
Noradrenaline is contraindicated in patients with known hypersensitivity to the drug or its excipients, and it should be used with extreme caution in individuals with uncontrolled hypertension, severe peripheral vascular disease, or those at high risk for tissue ischemia. Clinical judgment is required to assess suitability.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.
Send a sourcing enquiry for this product →

Product details

Drug
Noradrenaline Tartrate
Route
Intravenous Use
Manufacturer
Hospira Uk Limited,walton Oaks
Origin
EU

Related products

Cronomir

Cronomir

Noradrenaline Tartrate

Laboratoire Aguettant
EU
L-Noradrenalina Braun

L-Noradrenalina Braun

Noradrenaline Tartrate

B. Braun Medical Lda.
EU
Levophed

Levophed

Noradrenaline Tartrate

Hospira Benelux
EU
Levophed

Levophed

Noradrenaline Tartrate

Hospira Benelux
EU