Europe — EMA
Noradrenalina Tartrato (Norepinefrina) Aguettant (Noradrenaline Tartrate)
GNH USA supplies Noradrenalina Tartrato (Noradrenaline Tartrate), a vasopressor for hypotension, septic shock and cardiac arrest. Request a quote.
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What is Noradrenaline Tartrate?
Noradrenaline Tartrate, the active ingredient in Noradrenalina Tartrato (Aguettant), is a sympathomimetic (catecholamine) vasopressor presented as a solution for injection for intravenous use. It treats hypotension, septic shock, cardiogenic shock and cardiac arrest in hospitalized patients.
GNH USA supplies Noradrenalina Tartrato (Aguettant) as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, transplant centres, oncology centres, pharmacies and clinics worldwide.
What is Noradrenaline Tartrate used for?
Noradrenaline Tartrate is used in acute cardiovascular emergencies to restore vascular tone and cardiac output.
Hypotension: raises blood pressure in patients with acute low‑pressure states. Septic shock: increases systemic vascular resistance in septic shock. Cardiogenic shock: enhances myocardial contractility and perfusion. Cardiac arrest: supports circulation during resuscitation when combined with other emergency measures.
What are the side effects of Noradrenaline Tartrate?
Adverse reactions may occur with any vasopressor therapy.
Common Side Effects: - Tachycardia - Hypertension - Arrhythmias - Headache - Nausea - Peripheral ischemia
Serious or Rare Side Effects: - Myocardial ischemia - Severe hypertension - Tissue necrosis at injection site - Pulmonary edema - Life‑threatening arrhythmias - Anaphylactic reaction
What precautions apply to Noradrenaline Tartrate?
Noradrenaline Tartrate requires careful monitoring in critical care settings. - Blood pressure monitoring: continuous arterial pressure measurement is essential. - Cardiac disease: use with caution in patients with coronary artery disease or recent myocardial infarction. - Arrhythmias: avoid rapid infusion in patients with known arrhythmias. - Pheochromocytoma: contraindicated due to risk of hypertensive crisis. - Renal/hepatic impairment: dose adjustments may be needed. - Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.
What does Noradrenaline Tartrate interact with?
Noradrenaline Tartrate can interact with several drug classes.
Major Interactions (Avoid): - MAO inhibitors: risk of severe hypertensive crisis. - Beta‑blockers: may blunt the intended cardiovascular response. - Tricyclic antidepressants: additive catecholamine effects. - Local anesthetics: increased cardiotoxicity risk. - Vasodilators: may cause unpredictable blood pressure changes.
Moderate Interactions (Monitor Closely): - Calcium channel blockers: may enhance vasoconstrictive effects. - Diuretics: potential for volume depletion. - ACE inhibitors: possible additive hypotensive effect after tapering. - Other antihypertensives: monitor for excessive blood pressure rise. - Antifungal agents (azoles): may alter metabolism of catecholamines.



