Europe — EMA
Noradrenalin Fresenius Kabi (Noradrenaline Tartrate)
GNH USA supplies Noradrenalin Fresenius Kabi (Noradrenaline), a vasopressor for hypotension, septic shock and cardiac arrest.
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What is Noradrenaline Tartrate?
Noradrenaline, the active ingredient in Noradrenalin Fresenius Kabi, is a sympathomimetic agent presented as a solution for injection for intravenous use. It treats acute hypotension, septic shock and cardiac arrest in critical care settings.\n\nGNH India supplies Noradrenalin Fresenius Kabi as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals worldwide.
What is Noradrenaline Tartrate used for?
Noradrenalin Fresenius Kabi, a vasopressor acting on the sympathetic nervous system, is indicated for the following clinical situations:\n\n- Hypotension: raises systemic blood pressure in patients with acute low blood pressure.\n- Septic shock: improves hemodynamic stability in patients with severe infection‑induced circulatory failure.\n- Cardiac arrest: supports circulation during resuscitation efforts by increasing vascular tone and cardiac output.
What are the side effects of Noradrenaline Tartrate?
Adverse reactions may occur with intravenous norepinephrine therapy.\n\nCommon Side Effects:\n- Tachycardia: increased heart rate.\n- Arrhythmias: irregular cardiac rhythm.\n- Headache: mild to moderate intensity.\n- Peripheral ischemia: reduced blood flow to extremities.\n\nSerious or Rare Side Effects:\n- Severe hypertension: dangerously high blood pressure.\n- Myocardial ischemia: reduced oxygen supply to heart muscle.\n- Tissue necrosis: injury at the injection site if extravasation occurs.
What precautions apply to Noradrenaline Tartrate?
Use of Noradrenalin Fresenius Kabi requires careful clinical monitoring.\n\n- Monitor blood pressure: adjust infusion to maintain target pressures.\n- Monitor heart rate: watch for tachyarrhythmias.\n- Adjust infusion rate cautiously: titrate based on hemodynamic response.\n- Use central venous access for prolonged infusions: reduces risk of extravasation.\n- Contraindicated in patients with known hypersensitivity to noradrenaline.\n- Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.
What does Noradrenaline Tartrate interact with?
Noradrenalin Fresenius Kabi can interact with several drug classes.\n\nMajor Interactions (Avoid):\n- MAO inhibitors: may precipitate hypertensive crisis.\n- Beta‑blockers: can blunt the desired increase in heart rate.\n- Other vasopressors: additive pressor effect may cause severe hypertension.\n\nModerate Interactions (Monitor Closely):\n- ACE inhibitors: may enhance hypotensive episodes after infusion stops.\n- Diuretics: can affect intravascular volume and response to norepinephrine.\n- Calcium channel blockers: may influence vascular tone and heart rate.



