Europe — EMA
Noodanticonceptie Ulipristal Etos (Ulipristal Acetate)
GNH USA supplies Noodanticonceptie Ulipristal Etos (Ulipristal acetate), a selective progesterone receptor modulator for emergency contraception.
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What is Ulipristal Acetate?
Ulipristal acetate, the active ingredient in Noodanticonceptie Ulipristal Etos, is a selective progesterone receptor modulator presented as an oral tablet for oral use. It is employed as emergency contraception to prevent pregnancy when taken up to five days after unprotected intercourse in women of reproductive age.
GNH USA supplies Noodanticonceptie Ulipristal Etos as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, with a focus on quality assurance, regulatory compliance and reliable global logistics, and timely delivery.
What is Ulipristal Acetate used for?
Ulipristal acetate is a selective progesterone receptor modulator used in the emergency contraception pathway.
Emergency contraception (up to 5 days after unprotected intercourse): provides a non‑surgical option to prevent pregnancy by delaying or inhibiting ovulation. Contraceptive failure management: used when regular hormonal contraception fails, offering rapid pregnancy prevention. Missed oral contraceptive dose rescue: effective after a missed scheduled pill, reducing the risk of unintended conception.
What are the side effects of Ulipristal Acetate?
Ulipristal acetate is generally well tolerated, but several adverse reactions have been reported.
Common Side Effects: - Nausea - Headache - Abdominal or pelvic pain - Fatigue or dizziness - Menstrual irregularities (early, delayed or heavier bleeding) - Mild allergic skin reactions (rash, itching)
Serious or Rare Side Effects: - Anaphylactic or severe allergic reaction - Severe abdominal pain suggesting ectopic pregnancy - Liver enzyme elevation or hepatic injury - Persistent or worsening menstrual bleeding - Thromboembolic events (very rare) - Vision changes or severe headache indicating possible intracranial pressure changes
What precautions apply to Ulipristal Acetate?
When prescribing or dispensing Ulipristal acetate, consider the following safety measures.
Timing of administration: take as soon as possible, preferably within 120 hours after unprotected intercourse. Pregnancy status: avoid use if a confirmed pregnancy is present. Breastfeeding: consult a healthcare professional before use. Drug interactions: be aware of enzyme‑inducing agents that may lower effectiveness. Medical conditions: use with caution in patients with hepatic impairment. Store at ambient temperature: keep in the original packaging, protect from moisture and heat.
What does Ulipristal Acetate interact with?
Ulipristal acetate may interact with several concomitant medications.
Major Interactions (Avoid): - Rifampicin: strong enzyme inducer that markedly reduces efficacy. - St. John's wort: herbal inducer decreasing plasma levels. - Anticonvulsants (e.g., carbamazepine, phenytoin): lower drug exposure.
Moderate Interactions (Monitor Closely): - Hormonal contraceptives: may experience reduced effectiveness when taken together. - Antifungal azoles (e.g., ketoconazole): can increase ulipristal levels. - Certain antibiotics (e.g., tetracycline): minimal effect but monitoring is advised.



