Nolicin (Norfloxacin)

Norfloxacin, the active ingredient in Nolicin, is a fluoroquinolone presented as an oral tablet, typically available in standard strength tablets for systemic use. It is employed to treat bacterial infections such as uncomplicated urinary tract infections, acute prostatitis, certain gastrointestinal infections, and selected respiratory tract infections in adults.

GNH USA supplies Nolicin as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies, and clinics worldwide, with a focus on quality assurance, regulatory compliance, and reliable global logistics, and provides comprehensive support for regulatory documentation and post‑market surveillance.

Noricloxacin is a fluoroquinolone antibacterial that acts on susceptible bacterial infections.

- Uncomplicated urinary tract infection: eradicates the causative bacteria, relieving symptoms and preventing recurrence. - Acute prostatitis: eliminates the infecting organisms, aiding resolution of prostatic inflammation. - Bacterial gastroenteritis: targets susceptible gastrointestinal pathogens, reducing diarrhoea and abdominal discomfort. - Respiratory tract infections (e.g., bronchitis, pneumonia): clears susceptible respiratory pathogens, improving cough and fever.

Common Side Effects: - Nausea: mild to moderate upset stomach. - Diarrhoea: increased bowel movements, sometimes loose. - Headache: transient cranial discomfort. - Dizziness: sensation of light‑headedness or imbalance.

Serious or Rare Side Effects: - Tendon rupture: sudden pain and loss of function, especially in the Achilles. - QT interval prolongation: potential cardiac arrhythmia risk. - Severe allergic reaction: anaphylaxis with rash, swelling, or breathing difficulty.

Precautions should be observed when prescribing Noricloxacin. - Renal function: adjust therapy in patients with impaired kidney function. - Age: use cautiously in elderly patients due to increased susceptibility to adverse effects. - Concomitant corticosteroids: heightened risk of tendon injury. - History of QT prolongation: monitor cardiac rhythm. - Known hypersensitivity to fluoroquinolones: avoid use. - Store at room temperature: keep in the original container, protect from moisture and light.

Noricloxacin may interact with several medicines.

Major Interactions (Avoid): - Antacids containing aluminium or magnesium: markedly reduce Noricloxacin absorption. - Warfarin: may potentiate anticoagulant effect, increasing bleeding risk. - Theophylline: can raise serum theophylline concentrations, leading to toxicity. - Other fluoroquinolones (e.g., ciprofloxacin): additive toxicity, avoid co‑administration.

Moderate Interactions (Monitor Closely): - NSAIDs: may increase risk of central nervous system adverse effects. - Diabetes medications: possible alteration of glucose control. - Cyclosporine: may elevate cyclosporine levels, requiring monitoring.