GNH USA

Europe — EMA

Nolicin (Norfloxacin)

GNH USA supplies Nolicin (Norfloxacin), a fluoroquinolone for urinary tract infections, prostatitis, GI infections and travelers' diarrhea. Request a quote.

Norfloxacin

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What is Norfloxacin?

Norfloxacin, the active ingredient in Nolicin, is a fluoroquinolone presented as an oral tablet for systemic use. It treats bacterial infections of the urinary tract, prostate, gastrointestinal tract and travel‑related diarrhea in adult patients by inhibiting bacterial DNA replication.

GNH USA supplies Nolicin as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, ensuring consistent quality and regulatory compliance across EU and global markets.

What is Norfloxacin used for?

Noricloxacin is a fluoroquinolone antibacterial used to treat infections caused by susceptible bacteria. - Urinary tract infections: eradicates causative bacteria and resolves urinary symptoms. - Prostatitis: eliminates infection within prostate tissue and reduces associated inflammation. - Gastrointestinal infections: treats bacterial diarrhoea and dysentery, restoring normal gut function. - Travelers' diarrhea: provides rapid relief of acute bacterial diarrhea in travelers.

What are the side effects of Norfloxacin?

Common Side Effects: - Nausea: mild to moderate stomach upset. - Diarrhoea: loose stools occurring during therapy. - Headache: transient cranial discomfort. - Dizziness: sensation of light‑headedness. - Rash: mild skin erythema. - Abdominal pain: cramping or discomfort.

Serious or Rare Side Effects: - Tendon rupture: especially Achilles tendon, may occur during or after treatment. - Peripheral neuropathy: numbness or tingling in extremities. - QT interval prolongation: potential cardiac arrhythmia risk. - Severe allergic reactions: anaphylaxis, angioedema. - Clostridioides difficile infection: severe colitis. - Hepatic dysfunction: elevated liver enzymes or jaundice.

What precautions apply to Norfloxacin?

Precautions should be observed when prescribing Norfloxacin. - Renal impairment: adjust dose or monitor renal function closely. - Hepatic disease: use with caution; monitor liver enzymes. - Concomitant quinolones: avoid additive toxicity. - History of tendon disorders: avoid or monitor for tendon pain. - Pregnancy and breastfeeding: not recommended due to unknown safety. - Store at room temperature: keep in original container, protect from moisture and light.

What does Norfloxacin interact with?

Noricloxacin may interact with several medicines. Major Interactions (Avoid): - Antacids containing magnesium or aluminum: reduce Norfloxacin absorption. - Warfarin: may increase anticoagulant effect and bleeding risk. - Cyclosporine: increased cyclosporine levels leading to toxicity. - NSAIDs: heightened risk of central nervous system adverse effects. Moderate Interactions (Monitor Closely): - Oral contraceptives: reduced efficacy, consider backup method. - Diabetic agents: possible alteration of glucose control. - Theophylline: increased plasma concentrations, monitor for toxicity. - Corticosteroids: higher risk of tendon rupture, advise caution.

Frequently asked questions

What is Nolicin used for?+
Nolicin contains the fluoroquinolone antibiotic Norfloxacin and is prescribed to treat bacterial infections such as uncomplicated urinary tract infections, prostatitis, certain gastrointestinal infections and acute travelers' diarrhea caused by susceptible organisms.
How does Norfloxacin work?+
Norfloxacin blocks bacterial DNA gyrase and topoisomerase IV, enzymes required for DNA supercoiling and replication. Inhibiting these targets halts bacterial DNA synthesis, leading to bacterial cell death and a broad‑spectrum antibacterial effect.
What is the usual dose of Nolicin?+
The dosage of Nolicin is determined by the prescribing clinician based on the infection type, severity, patient age, renal function and other clinical factors. Patients should follow the prescriber’s instructions and not alter the dose on their own.
Is Nolicin safe in pregnancy or breastfeeding?+
Safety of Norfloxacin during pregnancy and lactation has not been established. Because potential risks cannot be ruled out, the drug is generally avoided in pregnant or breastfeeding women unless the benefits outweigh the risks and no safer alternative is available.
How do I order Nolicin from GNH USA?+
To order Nolicin, submit an enquiry on the product page at gnh-usa.com, specifying the required quantity. GNH USA works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.
How does Nolicin compare with other fluoroquinolones?+
Noricloxacin shares the same class mechanism as ciprofloxacin and levofloxacin but differs in its antimicrobial spectrum and pharmacokinetic profile. It is often chosen for infections where it demonstrates superior activity, such as certain urinary pathogens, while other fluoroquinolones may be preferred for respiratory or skin infections.
How should Nolicin be stored and handled?+
Store Nolicin at room temperature, below 25 °C, in the original blister or bottle. Keep the product away from moisture, direct sunlight and excessive heat. Do not use if the packaging is damaged or the tablets appear discoloured.
How is Nolicin administered?+
Nolicin is taken orally, usually with a full glass of water. It can be taken with or without food, but patients should avoid concurrent intake of antacids or supplements containing magnesium, aluminium or calcium, as these may reduce absorption.
What are the most serious risks associated with Nolicin?+
Serious adverse events include tendon rupture (especially Achilles), peripheral neuropathy, QT‑interval prolongation leading to cardiac arrhythmias, severe allergic reactions such as anaphylaxis, Clostridioides difficile‑associated colitis and hepatic injury. Patients should seek immediate medical attention if they experience any of these symptoms.
Who should not use Nolicin?+
Nolicin should be avoided in individuals with known hypersensitivity to Norfloxacin or other fluoroquinolones, in pregnant or breastfeeding women unless absolutely necessary, in children and adolescents for most indications, and in patients with a history of tendon disorders or significant cardiac QT prolongation.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.
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Product details

Drug
Norfloxacin
Route
Oral Use
Manufacturer
Krka-Farma D.O.O.
Origin
EU

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