GNH USA

Europe — EMA

Nogrip (Pheniramine Maleate, Ascorbic Acid, Paracetamol)

GNH USA supplies Nogrip (Pheniramine maleate, Ascorbic acid, Paracetamol), a combined antihistamine, analgesic and vitamin C for allergic rhinitis, headache

Pheniramine Maleate, Ascorbic Acid, Paracetamol

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What is Pheniramine Maleate, Ascorbic Acid, Paracetamol?

Pheniramine maleate, the active ingredient in Nogrip, is an H1‑receptor antagonist presented as an oral formulation for symptomatic relief of allergic rhinitis, headache, fever and common cold in adults and children. The product also contains paracetamol for analgesic and antipyretic action and ascorbic acid as an antioxidant, supporting overall symptom management.

GNH USA supplies Nogrip as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies, and clinics worldwide, ensuring quality and regulatory compliance across multiple markets through robust quality‑assured manufacturing and reliable distribution networks.

What is Pheniramine Maleate, Ascorbic Acid, Paracetamol used for?

Nogrip combines an antihistamine, an analgesic/antipyretic and vitamin C, acting on allergic and inflammatory pathways to relieve common cold‑related symptoms.

- Allergic rhinitis: reduces nasal congestion, itching and sneezing. - Common cold: alleviates runny nose, sore throat and general malaise. - Headache: provides analgesic relief of tension‑type headache. - Fever: lowers elevated body temperature associated with viral infections.

What are the side effects of Pheniramine Maleate, Ascorbic Acid, Paracetamol?

Adverse reactions to Nogrip may vary in frequency and severity.

Common Side Effects: - Drowsiness: mild sedation or sleepiness. - Dry mouth: reduced salivary flow causing throat discomfort. - Nausea: upset stomach or feeling of queasiness. - Dizziness: light‑headed sensation, especially on standing. - Headache: mild to moderate head pain. - Gastrointestinal upset: mild abdominal discomfort.

Serious or Rare Side Effects: - Anaphylaxis: severe allergic reaction with rash, swelling and breathing difficulty. - Hepatotoxicity: liver injury from excessive paracetamol exposure. - Blood disorders: rare cases of thrombocytopenia or neutropenia.

What precautions apply to Pheniramine Maleate, Ascorbic Acid, Paracetamol?

When considering Nogrip, several precautionary measures should be observed.

- Assess liver function: evaluate hepatic status before use due to paracetamol content. - Limit alcohol intake: avoid concurrent excessive alcohol to reduce liver risk. - Use caution in renal impairment: adjust dose or monitor if kidney disease is present. - Avoid in children under 12 years: not recommended without medical advice. - Pregnant or breastfeeding women: consult a healthcare professional before use. - Store at below 25°C: keep in the original pack, protect from moisture.

What does Pheniramine Maleate, Ascorbic Acid, Paracetamol interact with?

Nogrip can interact with other medicines; awareness of major and moderate interactions helps prevent adverse outcomes.

Major Interactions (Avoid): - Warfarin: paracetamol may increase anticoagulant effect and INR. - Other hepatotoxic drugs (e.g., isoniazid, methotrexate): additive risk of liver injury. - Heavy alcohol consumption: markedly raises risk of hepatic toxicity.

Moderate Interactions (Monitor Closely): - CNS depressants (e.g., benzodiazepines, opioids): may enhance sedation. - Additional antihistamines: can cause additive anticholinergic effects. - CYP450 substrates: paracetamol metabolism may alter levels of drugs processed by CYP2E1.

Frequently asked questions

What is Nogrip used for?+
Nogrip is formulated to provide symptomatic relief of allergic rhinitis, common cold, headache and fever. It combines an antihistamine, an analgesic/antipyretic and vitamin C to address nasal congestion, sneezing, sore throat, pain and elevated body temperature associated with viral upper‑respiratory infections.
How does Pheniramine maleate work?+
Pheniramine maleate is an H1‑receptor antagonist. By binding to histamine H1 receptors on mast cells and other tissues, it blocks the actions of histamine that cause itching, swelling, vasodilation and increased mucus production, thereby reducing the classic symptoms of allergic reactions.
What is the usual dose of Nogrip?+
The appropriate dose of Nogrip is determined by the prescribing healthcare professional based on the patient’s age, weight, clinical condition and any concomitant therapies. Patients should follow the prescriber’s instructions and the product label without altering the regimen on their own.
Is Nogrip safe during pregnancy or breastfeeding?+
Safety of Nogrip in pregnancy or lactation has not been fully established. Women who are pregnant, planning to become pregnant, or breastfeeding should discuss potential risks and benefits with their physician before using the product.
How do I order Nogrip from GNH USA?+
To place an order, submit an enquiry on the Nogrip product page at gnh-usa.com, specifying the required quantity. GNH USA works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.
How does Nogrip compare with other cold remedies?+
Unlike single‑ingredient decongestants, Nogrip offers a multi‑component approach: an antihistamine for allergic symptoms, paracetamol for pain and fever, and vitamin C for antioxidant support. This combination can simplify therapy by reducing the need for multiple separate products, while still addressing the key symptoms of a common cold.
How should Nogrip be stored?+
Nogrip should be stored at temperatures below 25 °C, in its original packaging, and protected from moisture and direct sunlight. Keeping the product in a dry, cool place helps maintain its stability and potency throughout its shelf life.
How is Nogrip administered?+
Nogrip is intended for oral use. The tablet (or other oral dosage form) should be swallowed whole with a glass of water, unless otherwise directed by a healthcare professional. It is usually taken with or without food, as advised by the prescriber.
What are the most serious risks to watch for?+
The most serious risks include severe allergic reactions such as anaphylaxis, and liver injury from excessive paracetamol exposure, especially when combined with alcohol or other hepatotoxic drugs. Patients should seek immediate medical attention if they experience rash, swelling, breathing difficulty, jaundice or unexplained fatigue.
Who should not use Nogrip?+
Individuals with known hypersensitivity to pheniramine, paracetamol, ascorbic acid or any excipients should avoid Nogrip. It is also contraindicated in patients with severe liver disease, uncontrolled asthma triggered by antihistamines, or in children for whom the dosage has not been established without medical guidance.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.
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Product details

Drug
Pheniramine Maleate, Ascorbic Acid, Paracetamol
Route
Oral Use
Manufacturer
Dr. Max Pharma S.R.O.
Origin
EU

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