GNH USA

Europe — EMA

Noctis Noc (Doxylamine Hydrogen Succinate)

GNH USA supplies Noctis Noc (Doxylamine), a first‑generation H1 antihistamine for short‑term insomnia and allergy relief. Request a quote for global supply.

Doxylamine Hydrogen Succinate

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What is Doxylamine Hydrogen Succinate?

Doxylamine, the active ingredient in Noctis Noc, is a first‑generation H1 antihistamine presented as an oral tablet for oral use. It is employed to alleviate short‑term insomnia and to relieve allergic symptoms such as rhinitis and urticaria in adults.

GNH USA supplies Noctis Noc as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides reliable logistics for global distribution. Customers benefit from consistent batch release, comprehensive documentation, and responsive technical support.

What is Doxylamine Hydrogen Succinate used for?

Doxylamine acts on histamine H1 receptors to provide sedative and antihistaminic effects.

- Insomnia: helps initiate and maintain sleep in adults with short‑term difficulty. - Allergic rhinitis: reduces nasal congestion, itching and sneezing associated with seasonal allergies. - Urticaria: alleviates itching and hives caused by allergic reactions.

What are the side effects of Doxylamine Hydrogen Succinate?

Doxylamine may cause a range of adverse reactions, varying from mild to serious.

Common Side Effects: - Drowsiness - Dry mouth - Blurred vision - Constipation

Serious or Rare Side Effects: - Anaphylaxis - Severe cardiac arrhythmia - Seizures - Hallucinations

What precautions apply to Doxylamine Hydrogen Succinate?

When using Noctis Noc, consider the following precautions: - Pregnancy: consult a healthcare professional before use. - Elderly: increased sensitivity to sedative effects. - Operating machinery: avoid driving or operating equipment until effects are known. - Alcohol: avoid concurrent consumption due to additive CNS depression. - Medical conditions: use cautiously in glaucoma, urinary retention, or COPD. - Store at ambient temperature: keep in the original container, protect from moisture and heat.

What does Doxylamine Hydrogen Succinate interact with?

Doxylamine can interact with several medicines; review the categories below.

Major Interactions (Avoid): - Alcohol: additive sedation and respiratory depression. - Opioids: enhanced CNS depression and risk of respiratory compromise. - Other CNS depressants (benzodiazepines, barbiturates): increased drowsiness and impaired coordination. - Anticholinergic drugs: cumulative anticholinergic burden may cause severe dry mouth, urinary retention.

Moderate Interactions (Monitor Closely): - Antihistamines (second‑generation): additive sedation. - CYP2D6 inhibitors (e.g., fluoxetine): may increase plasma levels of doxylamine. - Tricyclic antidepressants: additive anticholinergic effects. - SSRIs: potential for increased sedation.

Frequently asked questions

What is Noctis Noc used for?+
Noctis Noc contains doxylamine, which is used for short‑term treatment of insomnia and for relief of allergic symptoms such as rhinitis and urticaria. It helps people fall asleep and reduces itching, sneezing, and hives associated with allergic reactions.
How does doxylamine work?+
Doxylamine works by competitively blocking H1 histamine receptors in both peripheral tissues and the central nervous system. This antagonism reduces the actions of histamine that cause allergy symptoms and also produces a sedative effect that promotes sleep.
What is the usual dose of Noctis Noc?+
The appropriate dose of Noctis Noc is determined by a qualified healthcare professional based on the individual’s age, condition, and response to therapy. Patients should follow the prescriber’s instructions and not adjust the dose on their own.
Is Noctis Noc safe during pregnancy or breastfeeding?+
Safety information for doxylamine in pregnancy and lactation is limited. Women who are pregnant, planning to become pregnant, or breastfeeding should discuss potential risks and benefits with their doctor before using Noctis Noc.
How do I order Noctis Noc from GNH USA?+
To place an order, submit an enquiry on the product page at gnh-usa.com with the required quantity. GNH USA supplies hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.
How does Noctis Noc compare with other sleep aids like diphenhydramine?+
Both doxylamine and diphenhydramine are first‑generation antihistamines with sedative properties. Doxylamine generally has a longer half‑life, which may provide more sustained sleep support, while diphenhydramine may wear off earlier. Individual response varies, so clinicians choose the agent that best fits the patient’s needs.
How should Noctis Noc be stored?+
Store Noctis Noc at ambient temperature, below 25 °C. Keep the tablets in the original packaging, protect them from moisture, direct sunlight and excessive heat to maintain potency.
How is Noctis Noc administered?+
Noctis Noc is taken orally, usually with a full glass of water. It is intended for short‑term use, and patients should follow the timing and dosing instructions provided by their prescriber.
What are the most serious risks associated with Noctis Noc?+
Serious adverse reactions, although rare, include anaphylaxis, severe cardiac arrhythmias, seizures, and hallucinations. Anyone experiencing these symptoms should seek immediate medical attention.
Who should not use Noctis Noc?+
Individuals with known hypersensitivity to doxylamine or other first‑generation antihistamines, patients with severe glaucoma, urinary retention, or uncontrolled asthma, and those taking certain CNS depressants should avoid Noctis Noc unless advised otherwise by a healthcare professional.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.
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Product details

Drug
Doxylamine Hydrogen Succinate
Route
Oral Use
Manufacturer
Biofarm Sp. Z O.O.
Origin
EU

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