Europe — EMA
No-Spa Max (Drotaverine Hydrochloride)
GNH USA supplies No-Spa Max (Drotaverine Hydrochloride), a smooth muscle relaxant for abdominal pain, menstrual cramps and urinary colic. Request a quote.
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What is Drotaverine Hydrochloride?
Drotaverine Hydrochloride, the active ingredient in No‑Spa Max, is an antispasmodic (phosphodiesterase‑4 inhibitor) presented as an oral tablet for oral use. It is employed to relieve smooth‑muscle spasm‑related pain such as abdominal discomfort, menstrual cramps and urinary colic.
GNH USA supplies No‑Spa Max as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The product conforms to EU quality standards and is manufactured under GMP conditions.
What is Drotaverine Hydrochloride used for?
Drotaverine Hydrochloride acts as a smooth‑muscle relaxant and is indicated for conditions involving spasm of the gastrointestinal, genitourinary and vascular systems.
- Abdominal pain: reduces cramping and discomfort caused by intestinal spasms. - Menstrual cramps: alleviates uterine muscle contractions during dysmenorrhea. - Urinary colic: eases painful spasms of the urinary tract associated with renal colic or bladder obstruction.
What are the side effects of Drotaverine Hydrochloride?
Adverse reactions may occur with any antispasmodic medication.
Common Side Effects: - Headache: mild to moderate intensity. - Dizziness: transient sensation of light‑headedness. - Nausea: occasional upset stomach. - Dry mouth: reduced salivation. - Flushing: brief warmth or redness of the skin. - Gastro‑intestinal discomfort: mild abdominal upset.
Serious or Rare Side Effects: - Allergic reaction: rash, itching, swelling, or difficulty breathing. - Severe hypotension: sudden drop in blood pressure. - Cardiac arrhythmia: irregular heart rhythm. - Hepatic dysfunction: abnormal liver enzyme elevations. - Hematologic abnormalities: rare blood count changes.
What precautions apply to Drotaverine Hydrochloride?
Before using No‑Spa Max, consider the following safety measures.
- Pregnancy: consult a healthcare professional; safety data are limited. - Breastfeeding: discuss potential risks with a physician. - Liver impairment: use with caution; monitor hepatic function. - Renal impairment: dose adjustment may be required. - Concomitant antihypertensives: monitor blood pressure for additive effects. - Store at ambient temperature: keep below 25 °C, in the original packaging, protected from moisture and direct sunlight.
What does Drotaverine Hydrochloride interact with?
Drotaverine may interact with other medicines; awareness of potential interactions helps ensure safe use.
Major Interactions (Avoid): - Strong CYP3A4 inhibitors: may increase drotaverine plasma levels. - Antihypertensive agents: additive blood‑pressure‑lowering effect.
Moderate Interactions (Monitor Closely): - Other antispasmodics: risk of excessive smooth‑muscle relaxation. - Diuretics: monitor electrolyte balance. - Anticholinergic drugs: possible enhanced anticholinergic side effects.



