GNH USA

Europe — EMA

No-Spa (Drotaverine Hydrochloride)

GNH USA supplies No-Spa (Drotaverine Hydrochloride), an antispasmodic for abdominal pain, menstrual cramps and colic. Request a quote for global supply.

Drotaverine Hydrochloride

Request sourcing

1
Pack/s

What is Drotaverine Hydrochloride?

Drotaverine Hydrochloride, the active ingredient in No-Spa, is an antispasmodic presented as an oral tablet for oral use. It relaxes smooth muscle in the gastrointestinal, genitourinary and vascular systems and is used to alleviate abdominal pain, menstrual cramps, biliary and renal colic, and other spasm‑related conditions.

GNH USA supplies No-Spa as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

What is Drotaverine Hydrochloride used for?

Drotaverine Hydrochloride acts as a smooth‑muscle relaxant and is indicated for several spasm‑related conditions.

- Abdominal pain: Reduces cramping and discomfort in the stomach. - Menstrual cramps (dysmenorrhea): Alleviates uterine muscle spasms and associated pain. - Biliary colic: Relaxes biliary tract smooth muscle to ease gall‑bladder pain. - Renal colic: Relieves ureteral spasm and facilitates stone passage. - Gastro‑genitourinary spasm: Improves symptoms of smooth‑muscle irritation in the digestive and urinary tracts.

What are the side effects of Drotaverine Hydrochloride?

Adverse reactions may occur with any antispasmodic medication.

Common Side Effects: - Nausea: Mild to moderate stomach upset. - Dizziness: Transient light‑headedness. - Dry mouth: Reduced salivation. - Headache: Tension‑type headache. - Flushing: Warm sensation on the face or neck. - Gastro‑intestinal discomfort: Mild abdominal bloating.

Serious or Rare Side Effects: - Allergic reaction: Rash, itching, swelling, or anaphylaxis. - Severe hypotension: Marked drop in blood pressure. - Cardiac arrhythmia: Irregular heart rhythm. - Hepatic dysfunction: Elevated liver enzymes. - Hematologic changes: Unexplained bruising or bleeding. - Vision disturbances: Blurred or double vision.

What precautions apply to Drotaverine Hydrochloride?

Before using No‑Spa, consider the following safety measures.

- Pregnancy: Use only if clearly needed and prescribed by a healthcare professional. - Breastfeeding: Evaluate risk versus benefit with a physician. - Liver impairment: Monitor liver function and adjust use if necessary. - Kidney impairment: Caution in severe renal dysfunction. - Concomitant antihypertensives: Observe for additive blood‑pressure lowering effects. - Store at ambient temperature: Keep below 25 °C, retain in original packaging, and protect from moisture.

What does Drotaverine Hydrochloride interact with?

Drotaverine may interact with other medicines; monitor accordingly.

Major Interactions (Avoid): - Strong CYP3A4 inhibitors: May increase drotaverine plasma levels. - Antihypertensive agents: Potential additive hypotensive effect.

Moderate Interactions (Monitor Closely): - Anticholinergic drugs: May enhance dry‑mouth sensation. - Other antispasmodics: Increased risk of excessive smooth‑muscle relaxation. - Diuretics: Possible electrolyte imbalance when combined with hypotension. - NSAIDs: May increase gastrointestinal irritation risk.

Frequently asked questions

What conditions is No‑Spa used for?+
No‑Spa contains drotaverine hydrochloride, an antispasmodic that is commonly used to relieve abdominal pain, menstrual cramps (dysmenorrhea), biliary colic, renal colic, and other smooth‑muscle spasm conditions of the gastrointestinal and genitourinary tracts.
How does drotaverine work to relieve muscle spasms?+
Drotaverine inhibits the enzyme phosphodiesterase‑4, which raises intracellular cyclic AMP levels. The increased cAMP reduces calcium entry into smooth‑muscle cells, leading to muscle relaxation and a decrease in spasm‑related pain.
What is the usual dose of No‑Spa?+
The appropriate dose of No‑Spa is determined by a qualified prescriber based on the patient’s condition, age, weight, and overall health. Patients should follow the specific instructions provided by their healthcare professional.
Is No‑Spa safe to use during pregnancy or breastfeeding?+
Use of No‑Spa during pregnancy or while breastfeeding should only occur if the prescriber judges the benefit outweighs any potential risk. Women who are pregnant, planning pregnancy, or nursing should discuss safety with their doctor.
How do I order No‑Spa from GNH USA?+
To order No‑Spa, submit an enquiry on the product page at gnh-usa.com, specifying the required quantity. GNH USA supplies hospitals, pharmacies and procurement teams worldwide, and will request trade or institutional credentials before providing pricing, availability, shipping details and any necessary import documentation.
How does No‑Spa compare with other antispasmodic drugs?+
Compared with other antispasmodics such as hyoscine or papaverine, drotaverine has a selective phosphodiesterase‑4 inhibition mechanism, which may result in fewer anticholinergic side effects like dry mouth or blurred vision. Clinical choice depends on the specific indication, patient tolerance and physician preference.
What are the recommended storage conditions for No‑Spa?+
No‑Spa should be stored at ambient temperature, preferably below 25 °C. Keep the tablets in the original container, protect them from moisture and direct sunlight, and keep them out of reach of children.
How is No‑Spa administered?+
No‑Spa is taken orally, usually as a tablet. The tablet should be swallowed whole with a glass of water, unless the prescriber advises otherwise. Do not crush, chew, or dissolve the tablet unless instructed.
What are the most serious risks associated with No‑Spa?+
Serious risks, though rare, include severe allergic reactions (anaphylaxis), marked hypotension, cardiac arrhythmias, and significant liver enzyme elevations. Patients should seek immediate medical attention if they experience symptoms such as rash, swelling, faintness, rapid heartbeat, or jaundice.
Who should avoid using No‑Spa?+
Individuals with known hypersensitivity to drotaverine or any tablet excipients should not use No‑Spa. Caution is also advised for patients with severe liver or kidney impairment, uncontrolled hypertension, or those taking strong CYP3A4 inhibitors, unless a physician determines it is safe.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.
Send a sourcing enquiry for this product →

Product details

Drug
Drotaverine Hydrochloride
Route
Oral Use
Manufacturer
Opella Healthcare France Sas
Origin
EU

Related products

Antispasmin

Antispasmin

Drotaverine Hydrochloride

S C Biofarm S A
EU
Antispasmin Forte

Antispasmin Forte

Drotaverine Hydrochloride

S C Biofarm S A
EU
Dro Spaz

Dro Spaz

Drotaverine Hydrochloride

Adipharm Ead
EU
Drotafemme

Drotafemme

Drotaverine Hydrochloride

Sun-Farm Sp. Z.O.O.
EU