Nizoral (Ketoconazole)

Ketoconazole, the active ingredient in Nizoral, is an azole antifungal presented as a topical formulation for topical use. It treats common superficial fungal infections such as tinea corporis, tinea cruris, tinea pedis, seborrheic dermatitis and pityriasis versicolor in adults and children.\n\nGNH India supplies Nizoral as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Ketoconazole is an azole antifungal used to treat superficial fungal infections affecting the skin and scalp.\n\n- Tinea corporis: clears ring‑shaped skin lesions caused by dermatophytes.\n- Tinea cruris: resolves itching and redness in the groin area.\n- Tinea pedis: eliminates athlete's foot symptoms on the feet.\n- Seborrheic dermatitis: reduces flaking and erythema on the scalp and face.\n- Pityriasis versicolor: normalises skin pigmentation disrupted by Malassezia species.

Ketoconazole topical therapy may cause local skin reactions.\n\nCommon Side Effects:\n- Burning sensation: mild to moderate discomfort at the application site.\n- Itching: transient pruritus following use.\n- Redness: erythema localized to treated area.\n- Dryness: skin may feel less moisturised.\n- Peeling: superficial desquamation of skin.\n\nSerious or Rare Side Effects:\n- Severe allergic reaction: swelling, hives or difficulty breathing.\n- Contact dermatitis: intense rash or blistering.\n- Systemic absorption leading to hepatotoxicity: rare but possible with extensive use.

Before using Nizoral, consider the following precautions.\n\n- Avoid occlusive dressings: may increase systemic absorption.\n- Do not apply to broken skin: risk of irritation.\n- Limit use to prescribed area: avoid spreading to unaffected skin.\n- Monitor for allergic reactions: discontinue if severe rash develops.\n- Pregnancy and lactation: consult healthcare professional before use.\n- Store below 25°C: keep in original container, protect from moisture and direct sunlight.

Ketoconazole topical can interact with certain substances and treatments.\n\nMajor Interactions (Avoid):\n- Oral ketoconazole: additive risk of hepatotoxicity.\n- Systemic azole antifungals (e.g., itraconazole): may increase systemic exposure.\n\nModerate Interactions (Monitor Closely):\n- Concurrent topical corticosteroids: may enhance skin irritation.\n- Occlusive dressings: can raise systemic absorption.\n- Alcohol‑based skin products: may affect barrier function and increase irritation.