Nizoral (Ketoconazole)

Ketoconazole, the active ingredient in Nizoral, is an azole antifungal presented as a topical formulation for skin and scalp use. It treats fungal infections of the skin and scalp in adults and children as directed by a healthcare professional.

GNH USA supplies Nizoral as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Ketoconazole acts on fungal organisms that cause skin and scalp disorders, providing antifungal therapy for several common conditions.

- Seborrheic dermatitis: reduces inflammation and fungal overgrowth on the scalp and face. - Tinea corporis (ringworm): treats dermatophyte skin infections. - Tinea versicolor: clears Malassezia yeast causing discoloration of the skin.

Ketoconazole may cause local skin reactions when applied topically.

Common Side Effects: - Skin irritation: mild burning or stinging at the application site. - Itching: localized pruritus. - Dryness: reduced skin moisture. - Redness: erythema of the treated area. - Flaking: scaling of the skin. - Tingling sensation.

Serious or Rare Side Effects: - Severe allergic reaction: angioedema or anaphylaxis. - Contact dermatitis: intense rash and swelling. - Hair loss: unexpected shedding of hair. - Bullous eruption: blister formation. - Systemic absorption leading to liver enzyme changes (very rare).

Before using Nizoral, consider the following safety measures.

- Avoid use on broken or inflamed skin: may increase irritation. - Do not apply near eyes or mucous membranes: can cause discomfort. - Discontinue if severe irritation occurs: seek medical advice. - Consult a healthcare professional before use in children: dosing may differ. - Store at ambient temperature: keep in the original pack, protect from moisture and direct sunlight.

Ketoconazole can interact with other topical agents and systemic medications.

Major Interactions (Avoid): - Concurrent use with other topical antifungals: may increase local irritation. - Combination with potent corticosteroid creams: can mask infection signs.

Moderate Interactions (Monitor Closely): - Use with systemic ketoconazole (oral): may raise systemic exposure. - Application before hair dyeing: may reduce efficacy of the dye. - Co‑application with alcohol‑based products: can increase skin dryness.