GNH USA

Europe — EMA

Nitrolingual (Glyceryl Trinitrate)

GNH USA supplies Nitrolingual (Glyceryl Trinitrate), an organic nitrate for angina pectoris and prophylaxis of attacks. Request a quote for worldwide supply.

Glyceryl Trinitrate

Request sourcing

1
Pack/s

What is Glyceryl Trinitrate?

Glyceryl trinitrate, the active ingredient in Nitrolingual, is an organic nitrate presented as a sublingual spray for sublingual use. It treats acute angina pectoris and is employed for prophylaxis of angina attacks in adults, acting as a nitric‑oxide donor to reduce myocardial oxygen demand.

GNH USA supplies Nitrolingual as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

What is Glyceryl Trinitrate used for?

Nitrolingual, an organic nitrate, is used in the management of coronary artery disease‑related chest pain.

Acute angina pectoris: provides rapid relief of chest pain by vasodilation. Prophylaxis of angina attacks: reduces frequency of recurrent episodes when taken before exertion or stress.

What are the side effects of Glyceryl Trinitrate?

Nitrolingual may cause a range of adverse reactions, most of which are related to its vasodilatory properties.

Common Side Effects: - Headache: throbbing pain often described as tension‑type. - Flushing: warmth and redness of the face or neck. - Dizziness or light‑headedness: due to transient blood pressure drop. - Nausea: mild gastrointestinal upset.

Serious or Rare Side Effects: - Severe hypotension: marked drop in blood pressure that can lead to syncope. - Allergic reaction: rash, itching, swelling, or anaphylaxis in rare cases.

What precautions apply to Glyceryl Trinitrate?

When prescribing Nitrolingual, clinicians should observe several precautions to minimise risk.

- Avoid use in patients with severe hypotension: risk of further blood pressure reduction. - Do not combine with phosphodiesterase‑5 inhibitors: may cause profound hypotension. - Use cautiously in patients with anemia: can exacerbate symptoms of low oxygen delivery. - Monitor for tolerance development: efficacy may diminish with continuous use. - Store at ambient temperature below 25°C: keep in the original pack, protect from moisture and light.

What does Glyceryl Trinitrate interact with?

Nitrolingual can interact with other medicines, altering its effect or safety profile.

Major Interactions (Avoid): - Phosphodiesterase‑5 inhibitors (e.g., sildenafil, tadalafil): risk of severe hypotension. - Other organic nitrates (e.g., isosorbide dinitrate): additive vasodilatory effect. - Sodium nitroprusside: excessive vasodilation leading to dangerous blood pressure fall.

Moderate Interactions (Monitor Closely): - Beta‑blockers: may mask tachycardia that signals hypotension. - Antihypertensive agents (e.g., ACE inhibitors, calcium channel blockers): additive blood pressure lowering. - Alcohol: can enhance hypotensive response.

Frequently asked questions

What is Nitrolingual used for?+
Nitrolingual is prescribed to relieve acute episodes of angina pectoris and to prevent recurrent angina attacks in patients with coronary artery disease. It provides rapid sublingual delivery of glyceryl trinitrate, a vasodilator that eases chest pain by improving blood flow to the heart.
How does glyceryl trinitrate work?+
Glyceryl trinitrate releases nitric oxide after absorption. Nitric oxide activates guanylate cyclase, raising cyclic GMP levels in vascular smooth muscle. This cascade causes relaxation of arteries and veins, lowering cardiac preload and afterload, which reduces myocardial oxygen demand and alleviates angina symptoms.
What determines the dose of Nitrolingual?+
The dose of Nitrolingual is individualized by the prescribing clinician based on the severity of angina, patient response, and any concomitant therapies. The product is supplied as a sublingual spray, and the prescriber decides the number of sprays and frequency required for each patient.
Is Nitrolingual safe in pregnancy or breastfeeding?+
Safety data for glyceryl trinitrate during pregnancy and lactation are limited. The medication should only be used if the potential benefit justifies any possible risk to the fetus or infant. Healthcare providers should discuss individual circumstances with the patient before prescribing.
How do I order Nitrolingual from GNH USA?+
To request Nitrolingual, submit an enquiry on the product page at gnh-usa.com, specifying the required quantity. GNH USA works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.
How does Nitrolingual compare with other antianginal nitrates?+
Nitrolingual delivers glyceryl trinitrate via a sublingual spray, offering faster onset than oral tablets and more convenient dosing than sublingual tablets. Compared with other nitrates such as isosorbide dinitrate, it provides a rapid, short‑acting effect ideal for acute relief, while longer‑acting nitrates are used for maintenance therapy.
How should Nitrolingual be stored and handled?+
Nitrolingual should be stored at ambient temperature below 25 °C, protected from moisture, heat and direct sunlight. Keep the spray container tightly closed and retain it in its original packaging until use. Do not freeze or expose the product to extreme temperatures.
How is Nitrolingual administered?+
The patient places the prescribed number of sprays under the tongue and holds the medication there for several seconds without swallowing, allowing rapid absorption through the oral mucosa. The spray should be used only as directed by a healthcare professional, and the mouth should be rinsed after use if needed.
What are the most serious risks associated with Nitrolingual?+
The most serious risks include severe hypotension, which can cause fainting or shock, and rare allergic reactions such as rash, swelling or anaphylaxis. Patients should be monitored for signs of excessive blood pressure drop, especially when combined with other vasodilators, and seek immediate medical attention if serious symptoms develop.
Who should not use Nitrolingual?+
Nitrolingual is contraindicated in patients with known hypersensitivity to glyceryl trinitrate or any component of the formulation, and in those with severe hypotension or cardiogenic shock. Caution is also advised for individuals using phosphodiesterase‑5 inhibitors, as the combination can lead to dangerous blood pressure reductions.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.
Send a sourcing enquiry for this product →

Product details

Drug
Glyceryl Trinitrate
Route
Sublingual Use
Manufacturer
G. Pohl-Boskamp Gmbh Co. Kg
Origin
EU

Related products

Adesitrin

Adesitrin

Glyceryl Trinitrate

Merus Labs Luxco Ii S.À R.L.
EU
Cordiplast

Cordiplast

Glyceryl Trinitrate

Merus Labs Luxco Ii S.À R.L.
EU
Deponit

Deponit

Glyceryl Trinitrate

Merus Labs Luxco Ii S.À R.L.
EU
Deponit

Deponit

Glyceryl Trinitrate

Merus Labs Luxco Ii S.À R.L.
EU