Europe — EMA
Nitrofurantoin Pharmevid
GNH USA supplies Nitrofurantoin Pharmevid (Nitrofurantoin), a nitrofuran antibiotic for urinary tract infections and cystitis. Request a quote for supply.
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What is Nitrofurantoin?
Nitrofurantoin, the active ingredient in Nitrofurantoin Pharmevid, is a nitrofuran antibiotic presented as an oral tablet for oral use. It is employed to treat uncomplicated urinary tract infections, such as cystitis, in adult patients. The drug targets common uropathogens and is indicated for short‑course therapy to eradicate bacterial growth in the urinary tract.
GNH USA supplies Nitrofurantoin Pharmevid as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. Our distribution network ensures reliable access to quality‑assured medicines across diverse healthcare settings.
What is Nitrofurantoin used for?
Nitrofurantoin is a nitrofuran antibiotic used to treat infections of the urinary tract.
Uncomplicated urinary tract infection: eliminates causative bacteria, relieving symptoms and preventing progression. Cystitis: provides rapid bacterial eradication, reducing urinary discomfort and inflammation. Acute uncomplicated cystitis in women: short‑course therapy to achieve clinical cure. Recurrent uncomplicated UTI prophylaxis: may be used intermittently to reduce recurrence risk in selected patients.
What are the side effects of Nitrofurantoin?
Adverse reactions may occur with nitrofurantoin therapy.
Common Side Effects: - Nausea: mild stomach upset that may occur after dosing. - Loss of appetite: reduced desire to eat. - Diarrhea: loose stools, usually transient. - Headache: mild to moderate head pain.
Serious or Rare Side Effects: - Pulmonary toxicity: interstitial lung disease presenting with cough and dyspnea. - Hepatic injury: elevated liver enzymes or jaundice. - Severe allergic reaction: rash, swelling, or anaphylaxis. - Hemolytic anemia in G6PD deficiency: rapid drop in red blood cells.
What precautions apply to Nitrofurantoin?
Before prescribing nitrofurantoin, consider the following precautions. - Renal function: avoid in patients with severe renal impairment (eGFR <30 mL/min). - Pregnancy: category B, use only if clearly needed. - Breastfeeding: may be excreted in milk; assess risk‑benefit. - G6PD deficiency: risk of hemolysis; contraindicated. - Drug interactions: review concomitant medications for potential interactions. - Store at ambient temperature: keep in original container, protect from moisture and light.
What does Nitrofurantoin interact with?
Nitrofurantoin may interact with other medicines; monitor accordingly.
Major Interactions (Avoid): - Antacids containing magnesium or aluminum: reduce absorption. - Probenecid: may increase nitrofurantoin levels, risk of toxicity. - Cimetidine: may increase serum concentrations. - Fluoroquinolones: concurrent use may increase risk of pulmonary toxicity.
Moderate Interactions (Monitor Closely): - Warfarin: may enhance anticoagulant effect, monitor INR. - Diuretics: may affect renal clearance, monitor renal function. - Macrolide antibiotics: potential additive gastrointestinal upset.
Frequently asked questions
What is Nitrofurantoin Pharmevid used for?+
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