GNH USA

Europe — EMA

Nitrofurantoin Pharmevid

GNH USA supplies Nitrofurantoin Pharmevid (Nitrofurantoin), a nitrofuran antibiotic for urinary tract infections and cystitis. Request a quote for supply.

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What is Nitrofurantoin?

Nitrofurantoin, the active ingredient in Nitrofurantoin Pharmevid, is a nitrofuran antibiotic presented as an oral tablet for oral use. It is employed to treat uncomplicated urinary tract infections, such as cystitis, in adult patients. The drug targets common uropathogens and is indicated for short‑course therapy to eradicate bacterial growth in the urinary tract.

GNH USA supplies Nitrofurantoin Pharmevid as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. Our distribution network ensures reliable access to quality‑assured medicines across diverse healthcare settings.

What is Nitrofurantoin used for?

Nitrofurantoin is a nitrofuran antibiotic used to treat infections of the urinary tract.

Uncomplicated urinary tract infection: eliminates causative bacteria, relieving symptoms and preventing progression. Cystitis: provides rapid bacterial eradication, reducing urinary discomfort and inflammation. Acute uncomplicated cystitis in women: short‑course therapy to achieve clinical cure. Recurrent uncomplicated UTI prophylaxis: may be used intermittently to reduce recurrence risk in selected patients.

What are the side effects of Nitrofurantoin?

Adverse reactions may occur with nitrofurantoin therapy.

Common Side Effects: - Nausea: mild stomach upset that may occur after dosing. - Loss of appetite: reduced desire to eat. - Diarrhea: loose stools, usually transient. - Headache: mild to moderate head pain.

Serious or Rare Side Effects: - Pulmonary toxicity: interstitial lung disease presenting with cough and dyspnea. - Hepatic injury: elevated liver enzymes or jaundice. - Severe allergic reaction: rash, swelling, or anaphylaxis. - Hemolytic anemia in G6PD deficiency: rapid drop in red blood cells.

What precautions apply to Nitrofurantoin?

Before prescribing nitrofurantoin, consider the following precautions. - Renal function: avoid in patients with severe renal impairment (eGFR <30 mL/min). - Pregnancy: category B, use only if clearly needed. - Breastfeeding: may be excreted in milk; assess risk‑benefit. - G6PD deficiency: risk of hemolysis; contraindicated. - Drug interactions: review concomitant medications for potential interactions. - Store at ambient temperature: keep in original container, protect from moisture and light.

What does Nitrofurantoin interact with?

Nitrofurantoin may interact with other medicines; monitor accordingly.

Major Interactions (Avoid): - Antacids containing magnesium or aluminum: reduce absorption. - Probenecid: may increase nitrofurantoin levels, risk of toxicity. - Cimetidine: may increase serum concentrations. - Fluoroquinolones: concurrent use may increase risk of pulmonary toxicity.

Moderate Interactions (Monitor Closely): - Warfarin: may enhance anticoagulant effect, monitor INR. - Diuretics: may affect renal clearance, monitor renal function. - Macrolide antibiotics: potential additive gastrointestinal upset.

Frequently asked questions

What is Nitrofurantoin Pharmevid used for?+
Nitrofurantoin Pharmevid is indicated for the treatment of uncomplicated urinary tract infections, including acute cystitis, in adult patients. It targets common uropathogenic bacteria, helping to relieve urinary symptoms and prevent infection progression.
How does nitrofurantoin work?+
Nitrofurantoin is converted by bacterial nitroreductases into reactive intermediates that damage bacterial DNA and other macromolecules. This oxidative injury disrupts essential cellular processes, leading to bacterial cell death and eradication of the infection.
What is the usual dose of Nitrofurantoin Pharmevid?+
The dosage regimen for Nitrofurantoin Pharmevid is determined by the prescribing clinician based on the patient’s condition, renal function, and local treatment guidelines. Patients should follow the prescriber’s instructions and not alter the dose on their own.
Is Nitrofurantoin Pharmevid safe in pregnancy or breastfeeding?+
Nitrofurantoin is classified as pregnancy category B, indicating no evidence of risk in animal studies but limited human data. It may be used during pregnancy only when clearly needed. Small amounts can be excreted in breast milk, so a risk‑benefit assessment is recommended for nursing mothers.
How do I order Nitrofurantoin Pharmevid from GNH USA?+
To place an order, submit an enquiry on the product page at gnh-usa.com, specifying the required quantity. GNH USA supplies hospitals, pharmacies, and procurement teams worldwide, and will request verification of trade or institutional credentials before providing pricing, availability, shipping details, and any necessary import documentation.
How does Nitrofurantoin compare with the main alternative antibiotic?+
The most common alternative for uncomplicated urinary tract infections is trimethoprim‑sulfamethoxazole (TMP‑SMX). Nitrofurantoin has a narrower spectrum focused on urinary pathogens and is less likely to promote resistance in gut flora, but it requires adequate renal function for urinary concentration, whereas TMP‑SMX can be used in a broader range of renal function.
What are the storage and handling requirements for Nitrofurantoin Pharmevid?+
Nitrofurantoin Pharmevid should be stored at ambient temperature, below 25 °C, in its original packaging. Protect the tablets from moisture, direct sunlight, and excessive heat to maintain potency throughout the shelf life.
How is Nitrofurantoin Pharmevid administered?+
The medication is supplied as oral tablets that should be swallowed whole with a full glass of water. It may be taken with or without food, but taking it with food can reduce gastrointestinal discomfort in some patients.
What are the most serious risks associated with Nitrofurantoin Pharmevid?+
Serious adverse events include pulmonary toxicity (interstitial lung disease), hepatic injury (elevated liver enzymes or jaundice), severe allergic reactions such as anaphylaxis, and hemolytic anemia in patients with glucose‑6‑phosphate dehydrogenase (G6PD) deficiency. Prompt medical attention is required if any of these symptoms develop.
Who should not use Nitrofurantoin Pharmevid?+
Nitrofurantoin is contraindicated in patients with severe renal impairment (eGFR <30 mL/min), known hypersensitivity to nitrofurantoin or other nitrofurans, and individuals with G6PD deficiency due to risk of hemolysis. Caution is also advised for pregnant women, breastfeeding mothers, and patients with a history of pulmonary or hepatic disease.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Nitrofurantoin
Route
Oral Use
Manufacturer
Pharmevid S.R.O.
Origin
EU

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