Europe — EMA
Nitrofurantoin Iasis Pharma
GNH USA supplies Nitrofurantoin Iasis Pharma (Nitrofurantoin), a nitrofuran antibiotic for uncomplicated urinary tract infections. Request a quote for supply.
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What is Nitrofurantoin?
Nitrofurantoin, the active ingredient in Nitrofurantoin Iasis Pharma, is a nitrofuran antibiotic presented as an oral dosage form for oral use. It treats uncomplicated urinary tract infections and may be used for prophylaxis of recurrent infections in appropriate patients.
GNH USA supplies Nitrofurantoin Iasis Pharma as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.
What is Nitrofurantoin used for?
Nitrofurantoin Iasis Pharma is a nitrofuran antibiotic used to manage infections of the urinary tract. - Uncomplicated urinary tract infection: eradicates susceptible bacteria causing bladder infection. - Acute cystitis: provides rapid bactericidal activity to resolve bladder infection symptoms. - Prophylaxis of recurrent urinary tract infection: reduces the frequency of future infections when taken as preventive therapy.
What are the side effects of Nitrofurantoin?
Nitrofurantoin may cause a range of adverse reactions.
Common Side Effects: - Nausea: mild to moderate stomach upset. - Loss of appetite: reduced desire to eat. - Headache: transient cranial discomfort. - Diarrhea: loose stools, often self‑limiting. - Metallic taste: transient alteration of taste perception. - Rash: mild skin irritation or erythema.
Serious or Rare Side Effects: - Pulmonary toxicity: interstitial lung disease or acute respiratory distress. - Hepatic injury: elevated liver enzymes or hepatitis. - Hemolytic anemia in G6PD deficiency: rapid destruction of red blood cells. - Severe allergic reaction: anaphylaxis or angioedema. - Peripheral neuropathy: tingling or numbness in extremities. - Stevens‑Johnson syndrome: severe skin blistering and mucosal involvement.
What precautions apply to Nitrofurantoin?
Before prescribing Nitrofurantoin Iasis Pharma, clinicians should consider several safety factors. - Renal function assessment: avoid use in patients with creatinine clearance <30 mL/min. - G6PD deficiency: contraindicated due to risk of hemolysis. - Pregnancy trimester: avoid in late (third) pregnancy. - Monitor pulmonary symptoms: discontinue if respiratory distress develops. - Hepatic impairment: use with caution in severe liver disease. - Store below 25°C: keep in the original pack, protect from moisture and direct sunlight.
What does Nitrofurantoin interact with?
Nitrofurantoin Iasis Pharma can interact with other medicines, requiring attention to avoid reduced efficacy or increased toxicity.
Major Interactions (Avoid): - Antacids containing magnesium or aluminum: decrease nitrofurantoin absorption. - Probenecid: increases nitrofurantoin plasma levels, raising toxicity risk. - Warfarin: may enhance anticoagulant effect, increasing bleeding risk.
Moderate Interactions (Monitor Closely): - Fluoroquinolones: additive gastrointestinal upset. - Non‑steroidal anti‑inflammatory drugs (NSAIDs): potential renal function impact. - Diuretics: may alter urinary concentration, affecting drug efficacy.
Frequently asked questions
What is Nitrofurantoin Iasis Pharma used for?+
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