Nitrofurantoin Aurobindo

Nitrofurantoin, the active ingredient in Nitrofurantoin Aurobindo, is a nitrofuran antibiotic presented as an oral tablet for oral use. It treats uncomplicated urinary tract infections (cystitis) in adult patients. GNH USA supplies Nitrofurantoin Aurobindo as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Nitrofurantoin is a nitrofuran antibiotic used to treat infections of the urinary tract.

Uncomplicated urinary tract infection (cystitis): eliminates susceptible bacteria causing bladder infection. Recurrent urinary tract infection prophylaxis: reduces recurrence in patients with a history of UTIs. Acute uncomplicated cystitis in women: provides rapid bactericidal activity in the urine.

Nitrofurantoin may cause a range of adverse reactions, most of which are mild and reversible.

Common Side Effects: - Nausea or vomiting - Loss of appetite - Diarrhea or abdominal cramping - Metallic taste in the mouth

Serious or Rare Side Effects: - Pulmonary toxicity, including interstitial pneumonitis - Hepatic injury or jaundice - Hemolytic anemia, especially in patients with G6PD deficiency - Severe allergic reactions such as Stevens‑Johnson syndrome

Before prescribing Nitrofurantoin, clinicians should consider several safety factors.

Renal function: assess creatinine clearance and avoid use in severe renal impairment. Pregnancy: category B; use only when benefits outweigh potential risks. G6PD deficiency: avoid due to risk of hemolysis. Elderly patients: monitor for pulmonary toxicity and renal function. Drug interactions: review concomitant medications for potential absorption issues. Store at room temperature: keep in original container, protect from moisture and direct sunlight.

Nitrofurantoin can interact with several medicines, requiring attention to avoid reduced efficacy or increased toxicity.

Major Interactions (Avoid): - Antacids containing magnesium or aluminum: markedly reduce nitrofurantoin absorption. - Probenecid: decreases urinary excretion, lowering urinary concentrations. - Warfarin: may potentiate anticoagulant effect and increase INR.

Moderate Interactions (Monitor Closely): - Diuretics: increase risk of crystalluria and renal irritation. - Ciprofloxacin: potential antagonistic effect on bacterial killing. - Methenamine: additive urinary irritation, may exacerbate side effects.