Europe — EMA
Nitrendypina Egis (Nitrendipine)
GNH USA supplies Nitrendypina Egis (Nitrendipine), a calcium channel blocker indicated for hypertension management in adults. Request a quote for supply.
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What is Nitrendipine?
Nitrendipine, the active ingredient in Nitrendypina Egis, is a calcium channel blocker presented as an oral tablet for oral use. It is employed to lower elevated blood pressure in adult patients diagnosed with hypertension by causing vasodilation of peripheral arteries.
GNH USA supplies Nitrendypina Egis as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, adhering to stringent quality standards and providing reliable global distribution.
What is Nitrendipine used for?
Nitrendipine acts on the vascular smooth muscle to manage high blood pressure.
Hypertension: reduces systolic and diastolic blood pressure in adult patients with essential hypertension.
What are the side effects of Nitrendipine?
Nitrendipine may cause a range of adverse reactions.
Common Side Effects: - Headache: mild to moderate headache. - Flushing: sensation of warmth and redness. - Dizziness: light‑headedness upon standing. - Peripheral edema: mild swelling of the ankles.
Serious or Rare Side Effects: - Severe hypotension: marked drop in blood pressure. - Hepatic dysfunction: elevated liver enzymes or hepatitis. - Allergic reaction: rash, pruritus, or anaphylaxis.
What precautions apply to Nitrendipine?
Before initiating therapy, consider the following precautions.
Monitor blood pressure regularly: ensure therapeutic effect without excessive lowering. Use caution in hepatic impairment: dose adjustment may be required. Avoid concurrent use with other potent antihypertensives: risk of additive hypotension. Assess for heart failure: monitor for worsening symptoms. Adjust dose in elderly patients: start at the lower end of the dosing range. Store at room temperature: keep in the original pack, protect from moisture and direct sunlight.
What does Nitrendipine interact with?
Nitrendipine can interact with several drug classes.
Major Interactions (Avoid): - Concurrent use with other antihypertensives may cause excessive hypotension. - Strong CYP3A4 inhibitors (e.g., ketoconazole) can increase plasma concentrations. - Grapefruit juice: may elevate drug levels and enhance effects.
Moderate Interactions (Monitor Closely): - CYP3A4 inducers (e.g., rifampicin) may reduce efficacy. - Diuretics: may enhance electrolyte disturbances. - Beta‑blockers: additive blood‑pressure‑lowering effect.
