Europe — EMA
Nirolex Febbre E Dolore Adulti (Paracetamol)
GNH USA supplies Nirolex Febbre E Dolore Adulti (Paracetamol), a analgesic/antipyretic for fever and mild to moderate pain. Request a quote for global supply.
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What is Paracetamol?
Paracetamol, the active ingredient in Nirolex Febbre E Dolore Adulti, is a Analgesic/Antipyretic presented as a rectal dosage form for rectal use. It treats fever and mild to moderate pain in adults.
GNH USA supplies Nirolex Febbre E Dolore Adulti as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.
What is Paracetamol used for?
Paracetamol is an analgesic/antipyretic that reduces fever and alleviates mild to moderate pain.
- Fever: lowers elevated body temperature. - Headache: relieves tension‑type headache. - Musculoskeletal pain: eases mild to moderate muscle or joint discomfort. - Dental pain: reduces pain after dental procedures. - Cold/flu symptoms: helps control fever and associated body aches.
What are the side effects of Paracetamol?
Paracetamol is generally well tolerated, but adverse reactions can occur.
Common Side Effects: - Nausea - Mild abdominal discomfort - Rash or mild skin irritation - Dizziness
Serious or Rare Side Effects: - Severe skin reactions such as Stevens‑Johnson syndrome - Hepatotoxicity, especially with overdose or chronic use - Blood disorders including agranulocytosis - Anaphylactic reactions - Severe hypotension
What precautions apply to Paracetamol?
Paracetamol should be used with attention to specific safety considerations.
- Assess liver function: avoid use in patients with severe hepatic impairment. - Avoid alcohol: concurrent consumption may increase risk of liver injury. - Monitor dosage in elderly: reduced metabolic capacity may require lower doses. - Check for allergy: discontinue if rash or hypersensitivity develops. - Store at ambient temperature: keep in the original pack, protect from moisture.
What does Paracetamol interact with?
Paracetamol can interact with several medicines; awareness helps prevent adverse outcomes.
Major Interactions (Avoid): - Warfarin: may increase bleeding risk. - Alcohol: potentiates hepatotoxicity. - Carbamazepine: may reduce paracetamol efficacy. - Isoniazid: increased risk of liver injury.
Moderate Interactions (Monitor Closely): - Antiepileptics (e.g., phenytoin): may alter plasma levels. - Oral contraceptives: may reduce effectiveness. - Rifampicin: may increase metabolism, reducing analgesic effect.
