GNH USA

Europe — EMA

Nirolex Febbre E Dolore (Paracetamol)

GNH USA supplies Nirolex Febbre E Dolore (Paracetamol), a antipyretic analgesic for fever and mild to moderate pain. Request a quote for global supply.

Paracetamol

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1
Pack/s

What is Paracetamol?

Paracetamol, the active ingredient in Nirolex Febbre E Dolore, is an analgesic presented as an oral tablet for oral use. It reduces fever and alleviates mild to moderate pain in children and adults. Its antipyretic and analgesic properties make it suitable for managing febrile episodes and discomfort associated with common ailments.

GNH USA supplies Nirolex Febbre E Dolore as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to EU quality standards and provides reliable distribution across multiple markets.

What is Paracetamol used for?

Paracetamol acts on the central nervous system to control fever and relieve pain, and is indicated for the following conditions:

- Fever: lowers elevated body temperature. - Headache: eases tension‑type and mild migraine pain. - Muscular pain: reduces soreness from strain or over‑use. - Toothache: provides temporary relief of dental discomfort. - Cold/flu symptoms: helps manage aches and chills associated with viral infections.

What are the side effects of Paracetamol?

Paracetamol is generally well tolerated, but adverse reactions can occur.

Common Side Effects: - Nausea: mild stomach upset after ingestion. - Rash: skin redness or mild itching. - Abdominal discomfort: occasional stomach pain.

Serious or Rare Side Effects: - Severe skin reactions: such as Stevens‑Johnson syndrome. - Liver toxicity: potentially leading to hepatic failure. - Blood disorders: including thrombocytopenia or neutropenia.

What precautions apply to Paracetamol?

When using Nirolex Febbre E Dolore, consider the following precautions:

- Assess liver function: avoid in patients with severe hepatic impairment. - Avoid excessive alcohol: may increase risk of hepatotoxicity. - Do not exceed recommended daily dose: risk of liver injury increases with overdose. - Use with caution in children: follow pediatric dosing guidelines. - Pregnancy and breastfeeding: consult a healthcare professional before use. - Store at ambient temperature: keep in the original pack, protect from moisture.

What does Paracetamol interact with?

Paracetamol may interact with other medicines; monitor the following:

Major Interactions (Avoid): - Concurrent use with strong CYP2E1 inhibitors: increased toxicity. - Combination with other hepatotoxic drugs: heightened risk of liver damage. - Alcohol intake: may amplify hepatotoxic effects.

Moderate Interactions (Monitor Closely): - Warfarin: may enhance anticoagulant effect, requiring INR monitoring. - Isoniazid: potential additive stress on liver function. - Carbamazepine: may reduce analgesic efficacy of paracetamol.

Frequently asked questions

What is Nirolex Febbre E Dolore used for?+
Nirolex Febbre E Dolore contains paracetamol and is used to reduce fever and relieve mild to moderate pain such as headaches, muscular aches, toothache, and discomfort associated with common colds or flu. It is an over‑the‑counter option for short‑term symptom management.
How does paracetamol work?+
Paracetamol works by inhibiting cyclooxygenase enzymes in the central nervous system, which lowers the production of prostaglandins that trigger fever and pain signals. This central action reduces the hypothalamic temperature set‑point and diminishes nociceptive transmission, providing antipyretic and analgesic effects.
What is the usual dose of Nirolex Febbre E Dolore?+
The appropriate dose of Nirolex Febbre E Dolore is determined by a qualified healthcare professional based on the patient’s age, weight, and clinical condition. Patients should follow the prescriber’s instructions and never exceed the recommended maximum daily amount.
Is Nirolex Febbre E Dolore safe during pregnancy or breastfeeding?+
Safety data for paracetamol in pregnancy and lactation are limited. Women who are pregnant or breastfeeding should consult their healthcare provider before using Nirolex Febbre E Dolore to weigh potential benefits against any possible risks to the fetus or infant.
How do I order Nirolex Febbre E Dolore from GNH USA?+
To place an order, submit an enquiry on the product page at gnh-usa.com specifying the required quantity. GNH USA works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.
How does Nirolex Febbre E Dolore compare with ibuprofen?+
Both paracetamol (Nirolex Febbre E Dolore) and ibuprofen relieve pain and fever, but ibuprofen also has anti‑inflammatory activity. Paracetamol is generally gentler on the stomach and does not affect platelet function, while ibuprofen may cause gastrointestinal irritation and should be used with caution in patients with ulcer risk.
How should Nirolex Febbre E Dolore be stored?+
Store Nirolex Febbre E Dolore at ambient temperature, preferably below 25 °C. Keep the tablets in their original packaging, protect them from moisture and direct sunlight, and ensure the container is tightly closed to maintain product stability.
How is Nirolex Febbre E Dolore administered?+
Nirolex Febbre E Dolore is taken orally with a glass of water. The tablet should be swallowed whole and not crushed or chewed unless specifically instructed by a healthcare professional. It can be taken with or without food.
What are the most serious risks associated with Nirolex Febbre E Dolore?+
The most serious risks include severe skin reactions such as Stevens‑Johnson syndrome, significant liver injury that can lead to hepatic failure, and rare blood disorders like thrombocytopenia. Prompt medical attention is required if any signs of these conditions appear.
Who should not use Nirolex Febbre E Dolore?+
Individuals with known hypersensitivity to paracetamol, severe liver disease, or those who have exceeded the maximum daily dose of paracetamol should avoid using Nirolex Febbre E Dolore. Children under the recommended age or weight limits should also not be given the product without professional guidance.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.
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Product details

Drug
Paracetamol
Route
Oral Use
Manufacturer
Almus S.R.L.
Origin
EU

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