GNH USA

Europe — EMA

Nimelid (Nimesulide)

GNH USA supplies Nimelid (Nimesulide), a nonsteroidal anti-inflammatory drug for pain, inflammation and fever. Request a quote for global supply to worldwide.

Nimesulide

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1
Pack/s

What is Nimesulide?

Nimesulide, the active ingredient in Nimelid, is a nonsteroidal anti-inflammatory drug (NSAID) presented as an oral tablet for oral use. It provides analgesic, anti‑inflammatory and antipyretic effects for adults with mild to moderate pain, inflammatory conditions and fever.

GNH USA supplies Nimelid as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

What is Nimesulide used for?

Nimesulide is indicated for conditions involving pain, inflammation and fever.

- Mild to moderate pain: reduces pain intensity in adults. - Osteoarthritis: alleviates joint inflammation and improves mobility. - Fever: lowers elevated body temperature. - Dysmenorrhea: relieves menstrual cramps.

What are the side effects of Nimesulide?

Nimesulide may cause a range of adverse reactions, from mild to serious.

Common Side Effects: - Gastrointestinal discomfort: nausea, abdominal pain or dyspepsia. - Headache: mild to moderate intensity. - Dizziness: transient sensation of light‑headedness. - Skin rash: mild erythema or itching.

Serious or Rare Side Effects: - Severe liver injury: elevated transaminases or hepatitis. - Stevens‑Johnson syndrome: severe skin and mucosal reactions. - Gastrointestinal bleeding: ulceration or hemorrhage that may be life‑threatening.

What precautions apply to Nimesulide?

Before prescribing Nimelid, clinicians should consider several safety measures.

- Assess liver function: obtain baseline hepatic enzymes and monitor periodically. - Avoid in patients with known hypersensitivity to nimesulide or other NSAIDs. - Use the lowest effective dose: limit duration to reduce gastrointestinal risk. - Monitor renal function: especially in elderly, dehydrated or renally impaired patients. - Store at ambient temperature: keep below 25 °C, retain original packaging, protect from moisture.

What does Nimesulide interact with?

Nimesulide can interact with several drug classes, requiring careful management.

Major Interactions (Avoid): - Concurrent use with other COX‑2 selective NSAIDs: increased risk of gastrointestinal bleeding. - Combination with anticoagulants (e.g., warfarin, heparin): heightened bleeding tendency. - Use with hepatotoxic agents (e.g., isoniazid, methotrexate): potential for severe liver injury.

Moderate Interactions (Monitor Closely): - Concomitant diuretics or ACE inhibitors: may impair renal function. - Combination with systemic corticosteroids: increased risk of gastric ulceration.

Frequently asked questions

What conditions is Nimelid used for?+
Nimelid, containing the NSAID nimesulide, is prescribed to manage mild to moderate pain, inflammatory disorders such as osteoarthritis, fever, and dysmenorrhea. It provides analgesic, anti‑inflammatory and antipyretic effects in adult patients.
How does nimesulide work in the body?+
Nimesulide selectively blocks the cyclooxygenase‑2 (COX‑2) enzyme, which reduces the production of prostaglandins responsible for pain, inflammation and fever. By targeting COX‑2 while sparing COX‑1, it aims to maintain efficacy with a lower risk of gastrointestinal irritation.
What is the usual dose of Nimelid?+
The appropriate dose of Nimelid is determined by the prescribing healthcare professional based on the patient’s condition, age, renal and hepatic function, and other individual factors. Patients should follow the prescriber’s instructions and not adjust the dose on their own.
Is Nimelid safe during pregnancy or breastfeeding?+
The safety of nimesulide in pregnancy and lactation has not been established. It is generally avoided in pregnant or nursing women unless the potential benefit outweighs the potential risk, and only under close medical supervision.
How do I order Nimelid from GNH USA?+
To request Nimelid, submit an enquiry on the product page at gnh-usa.com, specifying the required quantity. GNH USA works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.
How does Nimelid compare with other NSAIDs?+
Nimelid (nimesulide) is a COX‑2 selective NSAID, offering analgesic and anti‑inflammatory benefits similar to ibuprofen or diclofenac but with a theoretically lower risk of gastric irritation. However, it carries a distinct risk of liver toxicity, which requires periodic monitoring.
What are the storage requirements for Nimelid?+
Nimelid tablets should be stored at ambient temperature, preferably below 25 °C. Keep them in the original container, protect from moisture and direct sunlight, and ensure they are out of reach of children.
How is Nimelid administered?+
Nimelid is taken orally, usually with a full glass of water. It can be taken with or without food, but patients who experience stomach upset may benefit from taking it with meals. Swallow the tablet whole; do not crush or chew.
What are the most serious risks associated with Nimelid?+
The most serious risks include severe liver injury, potentially leading to hepatitis or liver failure, and rare but life‑threatening skin reactions such as Stevens‑Johnson syndrome. Prompt medical attention is required if signs of liver dysfunction or severe skin rash appear.
Who should not use Nimelid?+
Nimelid should be avoided in patients with known hypersensitivity to nimesulide or other NSAIDs, those with active or severe liver disease, severe renal impairment, and individuals who have experienced serious skin reactions to NSAIDs. It is also contraindicated in the third trimester of pregnancy.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.
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Product details

Drug
Nimesulide
Route
Oral Use
Manufacturer
S.C. Rompharm Company S.R.L.
Origin
EU

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