Niflugel (Niflumic Acid)

Niflumic Acid, the active ingredient in Niflugel, is a NSAID (fenamate) presented as a topical gel for skin application. It is used to alleviate localized inflammation and pain in musculoskeletal conditions and is applied directly to the affected area.\n\nGNH India supplies Niflugel as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Niflugel is a topical NSAID that targets inflammatory processes in the musculoskeletal system.\n\n- Musculoskeletal pain: provides localized relief of pain associated with sprains, strains and overuse injuries.\n- Tendonitis: reduces inflammation and discomfort in inflamed tendons.\n- Bursitis: alleviates swelling and pain in inflamed bursae.\n- Osteoarthritis flare‑ups: helps manage joint pain and stiffness in affected areas.

Topical Niflugel may cause skin‑related reactions and, rarely, systemic adverse events.\n\nCommon Side Effects:\n- Local skin irritation: burning or stinging sensation at the application site.\n- Redness: mild erythema where the gel is applied.\n- Itching: pruritus localized to the treated area.\n- Dryness: skin may become dry or flaky.\n- Contact dermatitis: mild allergic skin reaction.\n\nSerious or Rare Side Effects:\n- Severe allergic reaction: swelling, hives, or difficulty breathing.\n- Stevens‑Johnson syndrome or toxic epidermal necrolysis.\n- Systemic NSAID effects: gastrointestinal ulceration or bleeding if absorbed in significant amounts.\n- Renal impairment: reduced kidney function in susceptible individuals.

When using Niflugel, consider the following safety measures.\n\n- Assess skin integrity: ensure the skin is intact before application.\n- Avoid broken skin: do not apply to cuts, abrasions or open wounds.\n- Keep away from eyes and mucous membranes: avoid contact with eyes, mouth and genitals.\n- Limit duration: use only for the prescribed period, typically not exceeding 7‑10 days without medical review.\n- Concomitant systemic NSAIDs: avoid using other NSAIDs simultaneously to reduce risk of systemic toxicity.\n- Store at room temperature: keep in the original container, protect from moisture and direct heat.

Topical Niflugel can interact with other medicines, especially those affecting coagulation or systemic NSAID exposure.\n\nMajor Interactions (Avoid):\n- Systemic NSAIDs: combined use may increase risk of gastrointestinal bleeding.\n- Anticoagulants (e.g., warfarin): may enhance anticoagulant effect and bleeding risk.\n- Lithium: topical NSAIDs can raise serum lithium levels.\n\nModerate Interactions (Monitor Closely):\n- Corticosteroids: concurrent use may increase skin thinning.\n- Methotrexate: monitor for additive toxicity.\n- ACE inhibitors or diuretics: watch for renal function changes in susceptible patients.