Europe — EMA
Niferex (Ferrous (Ii) Glycine Sulfate Complex)
GNH USA supplies Niferex (Ferrous (II) Glycine Sulfate Complex), an iron supplement for prevention of iron deficiency and treatment of iron‑deficiency
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What is Ferrous (Ii) Glycine Sulfate Complex?
Ferrous (II) Glycine Sulfate Complex, the active ingredient in Niferex, is an iron supplement presented as an oral formulation for oral use. It is used to prevent and treat iron deficiency and iron‑deficiency anemia in individuals who require additional dietary iron.
GNH USA supplies Niferex as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.
What is Ferrous (Ii) Glycine Sulfate Complex used for?
Niferex is an oral iron supplement that addresses conditions related to insufficient iron availability. - Iron deficiency anemia: helps restore normal hemoglobin and red blood cell counts. - Prevention of iron deficiency: supports maintenance of adequate iron stores in at‑risk populations. - Anemia due to chronic blood loss: provides supplemental iron to compensate for ongoing losses.
What are the side effects of Ferrous (Ii) Glycine Sulfate Complex?
Iron supplementation can be associated with a range of adverse reactions.
Common Side Effects: - Nausea: mild to moderate stomach discomfort. - Constipation: reduced bowel movements. - Diarrhea: loose stools in some individuals. - Dark stools: harmless change in stool color. - Metallic taste: transient after ingestion.
Serious or Rare Side Effects: - Severe allergic reaction: rash, itching, swelling, or difficulty breathing. - Iron overload: symptoms of organ dysfunction in cases of excessive dosing. - Gastrointestinal bleeding: uncommon but serious. - Hypotension: rare, especially with rapid intravenous administration (not applicable to oral form).
What precautions apply to Ferrous (Ii) Glycine Sulfate Complex?
When using Niferex, consider the following safety measures. - Assess iron status: confirm deficiency before initiating therapy. - Monitor hemoglobin: periodic testing to avoid excess iron. - Pregnancy and lactation: use only if prescribed after risk‑benefit evaluation. - Drug interactions: separate dosing from antacids or calcium supplements. - Storage: Store below 25°C: keep in the original container, protect from moisture and direct sunlight.
What does Ferrous (Ii) Glycine Sulfate Complex interact with?
Iron supplements can affect the absorption or efficacy of other medications.
Major Interactions (Avoid): - Tetracycline antibiotics: chelation reduces antibiotic absorption. - Fluoroquinolones (e.g., ciprofloxacin): decreased antimicrobial effectiveness. - Levothyroxine: impaired thyroid hormone uptake.
Moderate Interactions (Monitor Closely): - Antacids containing aluminum or magnesium: may lower iron absorption. - Calcium supplements or dairy products: compete for intestinal uptake. - Proton pump inhibitors: may reduce gastric acidity and iron solubility.



