Nifedipine Teva

Nifedipine, the active ingredient in Nifedipine Teva, is a calcium channel blocker presented as a tablet for oral use. It treats hypertension and angina pectoris in adults. GNH USA supplies Nifedipine Teva as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Nifedipine is a dihydropyridine calcium channel blocker used to manage cardiovascular conditions.

Hypertension: lowers blood pressure by relaxing arterial smooth muscle. Angina pectoris: reduces myocardial oxygen demand by decreasing afterload. Coronary artery spasm: alleviates vasospasm and improves coronary blood flow.

Nifedipine may cause a range of adverse reactions, from mild to severe.

Common Side Effects: - Headache: mild to moderate intensity. - Flushing: warm sensation, often on the face and neck. - Peripheral edema: swelling of ankles or feet. - Dizziness or light‑headedness. - Nausea: occasional gastrointestinal upset. - Tachycardia: increased heart rate.

Serious or Rare Side Effects: - Severe hypotension: marked drop in blood pressure. - Myocardial infarction: rare but possible cardiac event. - Arrhythmias: abnormal heart rhythms. - Hepatic dysfunction: elevated liver enzymes. - Allergic reactions: rash, pruritus, or anaphylaxis. - Stevens‑Johnson syndrome: severe skin reaction.

Before initiating therapy, clinicians should evaluate patient‑specific factors and monitor for potential complications.

Monitor blood pressure: ensure adequate control without excessive drop. Assess cardiac function: especially in patients with existing heart disease. Avoid abrupt discontinuation: taper to prevent rebound hypertension. Use caution in hepatic impairment: metabolism may be reduced. Use caution in elderly patients: increased sensitivity to hypotension. Store at room temperature: keep in the original pack, protect from moisture.

Nifedipine can interact with several medicines, altering its effectiveness or safety profile.

Major Interactions (Avoid): - Strong CYP3A4 inhibitors (e.g., ketoconazole, itraconazole): increase plasma levels. - Concurrent use with other potent vasodilators (e.g., nitroglycerin): risk of severe hypotension. - Grapefruit juice: can raise nifedipine concentrations.

Moderate Interactions (Monitor Closely): - Beta‑blockers: may enhance bradycardia or hypotension. - Diuretics: may increase risk of electrolyte imbalance and low blood pressure.