Nifedipine Retard Teva

Nifedipine, the active ingredient in Nifedipine Retard Teva, is a calcium channel blocker presented as an oral tablet for oral use. It treats hypertension and angina pectoris by relaxing vascular smooth muscle and reducing cardiac workload.

GNH USA supplies Nifedipine Retard Teva as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Nifedipine is a calcium channel blocker used to manage conditions related to vascular tone and cardiac workload.

Hypertension: lowers elevated blood pressure and reduces risk of cardiovascular complications. Angina pectoris: relieves chest pain by improving myocardial oxygen supply. Chronic stable angina: decreases frequency of angina attacks and improves exercise tolerance.

Nifedipine may cause a range of adverse reactions, from mild to severe.

Common Side Effects: - Headache - Flushing - Peripheral edema - Dizziness

Serious or Rare Side Effects: - Severe hypotension - Myocardial infarction - Severe allergic reaction (e.g., anaphylaxis)

Before initiating therapy, consider the following safety measures.

Monitor blood pressure regularly: ensure therapeutic effect without excessive hypotension. Assess hepatic function: dose adjustment may be needed in liver impairment. Avoid abrupt discontinuation: taper to prevent rebound hypertension. Use caution in heart failure: monitor for worsening symptoms. Review concomitant medications: evaluate for additive hypotensive effects. Store at room temperature: keep in the original container, protect from moisture.

Nifedipine can interact with several drug classes; awareness helps prevent adverse outcomes.

Major Interactions (Avoid): - Strong CYP3A4 inhibitors (e.g., ketoconazole, itraconazole): increase nifedipine levels. - Grapefruit juice: markedly raises plasma concentration. - Other antihypertensives (e.g., beta‑blockers, ACE inhibitors): additive hypotensive effect. - Certain antiarrhythmics (e.g., quinidine): risk of arrhythmias. - Simultaneous use with other calcium channel blockers: may cause excessive vasodilation.

Moderate Interactions (Monitor Closely): - Diuretics: may enhance blood pressure lowering. - Digoxin: increased risk of digoxin toxicity. - Statins metabolized by CYP3A4 (e.g., atorvastatin): monitor for muscle toxicity.