GNH USA

Europe — EMA

Nidol (Nimesulide)

GNH USA supplies Nidol (Nimesulide), a non‑steroidal anti‑inflammatory drug for mild to moderate pain, osteoarthritis and dysmenorrhea.

Nimesulide

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What is Nimesulide?

Nimesulide, the active ingredient in Nidol, is a non‑steroidal anti‑inflammatory drug presented as an oral tablet for oral use. It relieves mild to moderate pain and inflammation in conditions such as osteoarthritis and dysmenorrhea. GNH USA supplies Nidol as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

What is Nimesulide used for?

Nidol (nimesulide) is used to manage pain and inflammation associated with several musculoskeletal and gynecologic conditions.

Mild to moderate pain: provides analgesic relief by reducing inflammatory mediators. Osteoarthritis: decreases joint inflammation and improves mobility. Dysmenorrhea: alleviates menstrual cramps through anti‑inflammatory action.

What are the side effects of Nimesulide?

Nidol may cause a range of adverse reactions. Monitoring and prompt reporting of any symptoms are recommended.

Common Side Effects: - Gastrointestinal discomfort or dyspepsia - Nausea or vomiting - Headache - Dizziness - Skin rash or pruritus

Serious or Rare Side Effects: - Hepatotoxicity, including elevated liver enzymes - Severe skin reactions such as Stevens‑Johnson syndrome - Gastrointestinal bleeding or ulceration - Acute renal impairment - Anaphylactic or severe allergic reactions

What precautions apply to Nimesulide?

Before prescribing Nidol, clinicians should consider several safety factors. - Hypersensitivity: avoid in patients with known allergy to nimesulide or other NSAIDs. - Hepatic impairment: use with caution and monitor liver function. - Renal disease: assess renal function and adjust use accordingly. - Elderly patients: increased risk of gastrointestinal complications; consider gastro‑protective measures. - Concomitant anticoagulants or other NSAIDs: evaluate bleeding risk before co‑administration. - Store at ambient temperature (below 25°C): keep in the original pack, protect from moisture.

What does Nimesulide interact with?

Nidol can interact with several drug classes, requiring careful management.

Major Interactions (Avoid): - Anticoagulants (e.g., warfarin): heightened bleeding risk. - Other NSAIDs or COX‑2 inhibitors: additive gastrointestinal toxicity. - Lithium: increased serum lithium concentrations. - Methotrexate: reduced clearance leading to toxicity.

Moderate Interactions (Monitor Closely): - Corticosteroids: increased risk of gastric ulceration. - SSRIs or other serotonergic agents: potential for bleeding. - Diuretics: possible reduction in renal perfusion and function.

Frequently asked questions

What is Nidol used for?+
Nidol contains nimesulide, an NSAID indicated for the relief of mild to moderate pain and inflammation. It is commonly prescribed for conditions such as osteoarthritis, acute musculoskeletal pain, and dysmenorrhea, helping patients achieve better functional comfort.
How does nimesulide work?+
Nimesulide works by preferentially inhibiting the cyclooxygenase‑2 (COX‑2) enzyme, which reduces the production of prostaglandins that mediate pain, fever, and inflammation. This selective action aims to maintain anti‑inflammatory efficacy while limiting COX‑1‑related gastrointestinal side effects.
What is the usual dose of Nidol?+
The exact dose of Nidol is determined by the prescribing clinician based on the patient’s condition, age, and overall health. Healthcare professionals follow local prescribing guidelines and adjust the regimen to achieve optimal pain control while minimizing risk.
Is Nidol safe during pregnancy or breastfeeding?+
Nidol is generally not recommended for use during pregnancy, especially in the third trimester, due to potential fetal risks. Limited data are available for breastfeeding mothers, and caution is advised; alternative therapies are usually preferred.
How do I order Nidol from GNH USA?+
To request Nidol, submit an enquiry on the product page at gnh-usa.com, specifying the required quantity. GNH USA works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.
How does Nidol compare with other NSAIDs?+
Compared with non‑selective NSAIDs, nimesulide offers a higher degree of COX‑2 selectivity, which may reduce the incidence of gastrointestinal irritation. However, it still carries risks of hepatic and renal effects, so clinicians weigh these factors against alternatives such as ibuprofen or diclofenac.
How should Nidol be stored and handled?+
Nidol should be stored at ambient temperature, preferably below 25 °C. Keep the tablets in their original packaging, protect them from moisture and direct sunlight, and ensure they are out of reach of children.
How is Nidol administered?+
Nidol is taken orally, usually with a full glass of water. It can be taken with or without food, but patients who experience stomach upset may benefit from taking it with meals as advised by their healthcare provider.
What are the most serious risks associated with Nidol?+
The most serious adverse events include hepatotoxicity, severe skin reactions such as Stevens‑Johnson syndrome, gastrointestinal bleeding or ulceration, and acute renal impairment. Patients should be instructed to seek immediate medical attention if they notice signs of liver dysfunction, rash, or gastrointestinal bleeding.
Who should not use Nidol?+
Nidol should be avoided in individuals with known hypersensitivity to nimesulide or other NSAIDs, those with active peptic ulcer disease, severe hepatic or renal impairment, and patients in the third trimester of pregnancy. Clinicians should also assess cardiovascular risk before prescribing.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.
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Product details

Drug
Nimesulide
Route
Oral Use
Manufacturer
Pannonpharma Kft.
Origin
EU

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