Nicotinell Fruit (Nicotine Polacrilex)

Nicotine Polacrilex, the active ingredient in Nicotinell Fruit, is a nicotine replacement therapy presented as a buccal delivery system for buccal use. It is intended to aid adult smokers in quitting by reducing nicotine withdrawal symptoms and cravings.

GNH USA supplies Nicotinell Fruit as a licensed, GDP-compliant international pharmaceutical supplier serving pharmacies and clinics worldwide.

Nicotinell Fruit is a nicotine replacement product that acts on nicotine dependence to support smoking cessation.

- Smoking cessation: helps adult smokers quit by alleviating withdrawal symptoms and reducing cravings. - Tobacco dependence: assists individuals who wish to cut down on cigarette consumption while transitioning away from smoking. - Relapse prevention: provides support for former smokers aiming to maintain long‑term abstinence.

Nicotinell Fruit may cause a range of adverse reactions, most of which are mild and transient.

Common Side Effects: - Mouth irritation or soreness - Hiccups - Nausea - Headache - Dizziness - Throat irritation

Serious or Rare Side Effects: - Allergic reaction (rash, swelling, difficulty breathing) - Oral ulceration or lesions - Increased blood pressure or palpitations - Chest pain - Severe nausea or vomiting - Unexplained fainting

Before using Nicotinell Fruit, consider the following safety measures.

- Assess nicotine dependence: evaluate smoking history and level of dependence prior to initiation. - Avoid use in non‑smokers: not indicated for individuals without nicotine addiction. - Monitor cardiovascular status: use with caution in patients with heart disease or hypertension. - Do not use with other nicotine products: avoid concurrent use of patches, gum, or e‑cigarettes. - Store at ambient temperature: keep in the original pack, protect from moisture and heat.

Nicotinell Fruit can interact with other medicines, requiring attention to avoid adverse outcomes.

Major Interactions (Avoid): - Monoamine oxidase inhibitors (MAOIs): may increase risk of hypertensive crisis. - Strong CYP2A6 inhibitors: can alter nicotine metabolism and increase systemic exposure.

Moderate Interactions (Monitor Closely): - Selective serotonin reuptake inhibitors (SSRIs): may heighten nausea. - Antihypertensive agents: nicotine may reduce their efficacy. - Alcohol: concurrent use can enhance nicotine’s cardiovascular effects.