Nicotinell Fruit (Nicotine Polacrilex)

Nicotine Polacrilex, the active ingredient in Nicotinell Fruit, is a nicotine replacement therapy presented as a buccal formulation for buccal use. It helps adult smokers reduce nicotine dependence and manage withdrawal symptoms to aid quitting tobacco use.

GNH USA supplies Nicotinell Fruit as a licensed, GDP-compliant international pharmaceutical supplier serving pharmacies and clinics worldwide.

Nicotinell Fruit provides nicotine polacrilex as a nicotine replacement therapy, targeting tobacco dependence and supporting cessation efforts.

- Smoking cessation: reduces cravings and withdrawal symptoms to aid quitting tobacco use. - Relapse prevention: supports maintaining abstinence after initial quitting by providing controlled nicotine exposure.

Common Side Effects: - Mouth irritation: mild soreness or tingling in the oral cavity. - Nausea: transient feeling of queasiness after use. - Increased salivation: excess saliva production during chewing. - Dyspepsia: occasional indigestion or stomach discomfort. - Taste disturbance: altered perception of flavors. - Hiccups: brief, involuntary diaphragm contractions.

Serious or Rare Side Effects: - Allergic reaction: rash, itching, or swelling indicating hypersensitivity. - Throat swelling: edema that may compromise airway. - Chest pain: unexplained discomfort requiring medical evaluation. - Irregular heartbeat: palpitations or arrhythmia. - Severe skin rash: widespread erythema or blistering. - Anaphylaxis: rare, life‑threatening systemic reaction.

Before initiating therapy, consider the following precautions: - Assess nicotine dependence: evaluate the level of addiction to tailor duration of use. - Allergy screening: avoid if known hypersensitivity to nicotine or formulation excipients. - Cardiovascular risk: do not use in patients with recent myocardial infarction or unstable angina. - Hypertension monitoring: use with caution in uncontrolled high blood pressure. - Duration limit: adhere to recommended treatment length to prevent prolonged nicotine exposure. - Store at ambient temperature: keep in the original pack, protect from moisture and direct sunlight.

Nicotine Polacrilex may interact with several medication classes.

Major Interactions (Avoid): - Monoamine oxidase inhibitors: increased risk of hypertensive crisis. - Beta‑blockers: nicotine may mask tachycardia, complicating cardiovascular monitoring. - Insulin: nicotine can alter glucose metabolism, affecting insulin requirements.

Moderate Interactions (Monitor Closely): - Caffeine: combined stimulant effect may increase nervousness. - Antidepressants: monitor for mood changes or heightened side effects. - Antihypertensives: nicotine may reduce blood‑pressure‑lowering efficacy.