Nicorette Freshfruit (Nicotine Polacrilex)

Nicotine polacrilex, the active ingredient in Nicorette Freshfruit, is a nicotine replacement therapy presented as a chewing gum for oromucosal use. It helps adults who want to quit smoking by reducing withdrawal symptoms and cravings. Nicotine polacrilex works by delivering a controlled dose of nicotine to the oral mucosa, providing a smoother transition away from cigarettes.

GNH USA supplies Nicorette Freshfruit as a licensed, GDP‑compliant international pharmaceutical supplier serving pharmacies and clinics worldwide.

Nicotine polacrilex chewing gum is used in nicotine replacement therapy to support smoking cessation.

- Smoking cessation: provides controlled nicotine to reduce cravings and withdrawal symptoms. - Relapse prevention: assists individuals who have quit smoking to maintain abstinence. - Reduction of smoking: helps smokers who wish to gradually decrease cigarette consumption.

Common Side Effects: - Mouth irritation or soreness: discomfort in the oral cavity during chewing. - Hiccups: involuntary diaphragm contractions after use. - Nausea or dyspepsia: mild gastrointestinal upset. - Increased salivation: excess saliva production. - Jaw discomfort: muscle fatigue from chewing. - Bad taste: lingering flavor after use.

Serious or Rare Side Effects: - Allergic reactions: rash, itching, swelling, or difficulty breathing. - Chest pain: unexpected cardiovascular discomfort. - Severe dizziness or fainting: notable drop in blood pressure. - Persistent vomiting: inability to retain food or fluids. - Throat swelling: airway obstruction risk. - Anaphylaxis: life‑threatening systemic allergic response.

Before using Nicotine polacrilex chewing gum, consider the following precautions: - Assess nicotine dependence: evaluate the need for nicotine replacement therapy. - Allergy check: do not use if known hypersensitivity to nicotine or gum ingredients. - Cardiovascular risk: avoid in recent myocardial infarction or unstable angina without medical advice. - Dosage limits: do not exceed the recommended chewing frequency advised by a healthcare professional. - Pregnancy and breastfeeding: consult a clinician as safety has not been established. - Store at room temperature: keep in the original pack, protect from moisture and heat.

Nicotine polacrilex may interact with other medicines, requiring attention to avoid adverse outcomes.

Major Interactions (Avoid): - Monoamine oxidase inhibitors (MAOIs): increased risk of cardiovascular events. - Other nicotine‑containing products: potential nicotine overdose. - CYP2A6 inhibitors (e.g., cimetidine): may raise nicotine plasma levels.

Moderate Interactions (Monitor Closely): - Beta‑blockers: nicotine can affect heart rate and blood pressure. - Antihypertensive agents: monitor for changes in blood pressure control. - Certain antidepressants (e.g., SSRIs): observe for mood alterations or increased side‑effects.