Nicorette Freshfruit (Nicotine)

Nicotine, the active ingredient in Nicorette Freshfruit, is a nicotine replacement therapy presented as an oromucosal product for oromucosal use. It is used to help adult smokers quit by reducing cravings and withdrawal symptoms associated with tobacco dependence.

GNH USA supplies Nicorette Freshfruit as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Nicotine replacement therapy such as Nicorette Freshfruit is used within the smoking cessation pathway to aid adults who wish to stop using tobacco.

- Smoking cessation: helps adult smokers quit by reducing cravings and withdrawal symptoms. - Tobacco dependence: provides controlled nicotine to support gradual reduction of tobacco use. - Nicotine addiction: assists in managing nicotine dependence during the quitting process.

Common Side Effects: - Mouth irritation or soreness - Throat irritation or dryness - Nausea or upset stomach - Hiccups - Headache - Dizziness

Serious or Rare Side Effects: - Allergic reaction (rash, itching, swelling) - Chest pain or palpitations - Irregular heartbeat - Severe mouth ulceration - Swelling of face, lips, or tongue - Anaphylaxis (rare but life‑threatening)

Precautions for Nicorette Freshfruit include careful consideration of patient health status and proper handling. - Medical guidance: Use under the direction of a healthcare professional. - Non‑smokers: Not intended for individuals who do not use tobacco. - Allergy: Avoid if known hypersensitivity to nicotine or product excipients. - Cardiovascular disease: Use with caution in patients with heart conditions. - Pregnancy and breastfeeding: Safety not established; consult a physician. - Store at room temperature: keep in original packaging, protect from moisture and direct sunlight.

Nicotine may interact with several medications; monitoring is advised.

Major Interactions (Avoid): - Theophylline: nicotine can increase clearance, reducing therapeutic effect. - MAO inhibitors: may potentiate hypertensive responses.

Moderate Interactions (Monitor Closely): - Clozapine: nicotine may raise plasma levels, requiring dose adjustment. - Insulin or oral hypoglycemics: nicotine can affect glucose control. - Beta‑blockers: nicotine may diminish antihypertensive efficacy. - CYP1A2 substrates (e.g., caffeine, warfarin): nicotine induces metabolism, potentially lowering drug concentrations.