Europe — EMA
Nicerin (Nicergoline)
GNH USA supplies Nicerin (Nicergoline), a vasodilator for cerebral vascular insufficiency, age‑related cognitive decline and dementia. Request a quote.
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What is Nicergoline?
Nicergoline, the active ingredient in Nicerin, is an ergoline derivative presented as an oral tablet for oral use. It acts as a cerebral vasodilator and cognitive enhancer, indicated for cerebral vascular insufficiency, age‑related cognitive decline, dementia and memory impairment.
GNH USA supplies Nicerin as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, with a focus on reliable supply chains.
What is Nicergoline used for?
Nicerin (nicergoline) is employed in the management of cerebral vascular and cognitive disorders.
- Cerebral vascular insufficiency: improves cerebral blood flow to alleviate symptoms of reduced perfusion. - Age‑related cognitive decline: supports memory and attention functions in elderly patients. - Dementia: used as an adjunct to help maintain cognitive performance. - Memory impairment: may enhance recall and learning capacity.
What are the side effects of Nicergoline?
Nicerin may be associated with a range of adverse reactions, varying from mild to serious.
Common Side Effects: - Headache: mild to moderate intensity. - Dizziness or vertigo. - Nausea or gastrointestinal discomfort. - Flushing or warmth sensation.
Serious or Rare Side Effects: - Severe hypotension with syncope. - Cardiac arrhythmias. - Hepatic dysfunction.
What precautions apply to Nicergoline?
When prescribing Nicerin, clinicians should consider several safety measures. - Renal or hepatic impairment: monitor function and adjust therapy as needed. - Elderly patients: start at a lower dose and observe for hypotension. - Concomitant antihypertensives: risk of additive blood‑pressure lowering. - History of bleeding disorders: assess risk due to antiplatelet activity. - Store at ambient temperature: keep below 25 °C, protect from moisture and light in the original packaging.
What does Nicergoline interact with?
Nicergoline can interact with several drug classes, requiring careful assessment.
Major Interactions (Avoid): - Combined use with other potent vasodilators: may cause severe hypotension. - Anticoagulants or antiplatelet agents: increased bleeding risk. - Monoamine‑oxidase inhibitors: potential hypertensive crisis.
Moderate Interactions (Monitor Closely): - Antihypertensive drugs: may enhance blood‑pressure lowering. - CYP450 inhibitors (e.g., erythromycin): may raise nicergoline plasma levels. - Central nervous system depressants: additive dizziness or sedation.
