Europe — EMA
NexGard
GNH USA supplies NexGard (Afoxolaner), a isoxazoline antiparasitic for flea and tick infestations in dogs. Request a quote for global supply to veterinarians.
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What is Afoxolaner?
Afoxolaner, the active ingredient in NexGard, is a isoxazoline presented as a chewable tablet for oral use. It treats flea and tick infestations in dogs by delivering systemic ectoparasite control through a single monthly dose, offering convenient and rapid protection.
GNH USA supplies NexGard as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, providing reliable sourcing for veterinary professionals seeking high‑quality antiparasitic solutions, ensuring compliance with regulatory standards and timely delivery across global markets for all customers.
What is Afoxolaner used for?
NexGard (afoxolaner) is an isoxazoline ectoparasiticide used to control external parasites in dogs.
Flea infestation: eliminates adult fleas and prevents new infestations for up to one month. Tick infestation: kills attached ticks and prevents attachment of new ticks for up to one month. Canine ectoparasite control: provides broad‑spectrum protection against common external parasites in dogs.
What are the side effects of Afoxolaner?
Adverse reactions reported with NexGard are generally mild, but veterinary monitoring is advised.
Common Side Effects: - Mild gastrointestinal upset: occasional vomiting or soft stools. - Transient lethargy: temporary reduced activity. - Reduced appetite: brief decrease in food intake.
Serious or Rare Side Effects: - Seizures: rare neurologic events. - Anaphylactic reactions: severe allergic response. - Severe dermatitis: intense skin inflammation.
What precautions apply to Afoxolaner?
When using NexGard, consider the following precautions: - Dosage determination: based on the dog's weight as prescribed by a veterinarian. - Age restriction: not recommended for puppies under 8 weeks or under 2 kg. - Concurrent medications: review potential interactions with other ectoparasitic products. - Health status: use with caution in dogs with known neurological disorders. - Pregnancy and lactation: safety not established; consult veterinarian. - Store at ambient temperature: keep below 25°C in the original packaging, protect from moisture.
What does Afoxolaner interact with?
Potential drug interactions with NexGard should be evaluated by a veterinarian.
Major Interactions (Avoid): - Co‑administration with other isoxazoline products: risk of additive neurotoxicity. - Concurrent use of strong CYP3A4 inhibitors: may increase afoxolaner exposure. - Use with phenobarbital: potential antagonism.
Moderate Interactions (Monitor Closely): - Combination with other flea/tick preventatives: monitor for additive side effects. - Concurrent use of certain antihistamines: may increase sedation.
Frequently asked questions
What is NexGard used for?+
How does afoxolaner work?+
What determines the usual dose of NexGard?+
Is NexGard safe for pregnant or nursing dogs?+
How do I order NexGard from GNH USA?+
How does NexGard compare with the main alternative drug or class?+
What are the storage and handling requirements for NexGard?+
How is NexGard administered to dogs?+
What are the most serious risks associated with NexGard?+
Who should not use NexGard?+
Product details
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