GNH USA

Europe — EMA

Nevralgio (Paracetamol, Acetylsalicylic Acid, Caffeine)

GNH USA supplies Nevralgio (Paracetamol/Aspirin/Caffeine), a combination analgesic and antipyretic for headache, fever and mild to moderate pain.

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What is Paracetamol, Acetylsalicylic Acid, Caffeine?

Paracetamol, Acetylsalicylic Acid and Caffeine, the active ingredients in Nevralgio, form an analgesic and antipyretic combination presented as an oral tablet for oral use. The product is intended to relieve mild to moderate pain and reduce fever in adults and adolescents.

GNH USA supplies Nevralgio as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to European Union quality standards and provides reliable global distribution.

What is Paracetamol, Acetylsalicylic Acid, Caffeine used for?

Nevralgio is used to manage pain and fever by acting on prostaglandin pathways.

- Headache: provides rapid relief of tension‑type and mild migraine pain. - Fever: reduces elevated body temperature in febrile conditions. - Mild to moderate pain: alleviates dental, musculoskeletal, and postoperative discomfort.

What are the side effects of Paracetamol, Acetylsalicylic Acid, Caffeine?

Like all medicines, Nevralgio may cause unwanted reactions.

Common Side Effects: - Nausea: mild stomach upset. - Gastric irritation: discomfort or heartburn. - Insomnia: difficulty sleeping due to caffeine. - Increased heart rate: mild palpitations.

Serious or Rare Side Effects: - Gastrointestinal bleeding: black stools or vomiting blood. - Allergic reaction: rash, itching, swelling, or difficulty breathing. - Liver toxicity: jaundice or elevated liver enzymes with excessive use.

What precautions apply to Paracetamol, Acetylsalicylic Acid, Caffeine?

Before using Nevralgio, consider the following safety measures. - Assess liver function: avoid use in patients with severe hepatic impairment. - Evaluate bleeding risk: caution in individuals with ulcers, anticoagulant therapy, or clotting disorders. - Monitor caffeine intake: limit additional stimulants to reduce insomnia or tachycardia. - Avoid use in children under 12 years: safety not established for this age group. - Pregnancy and breastfeeding: consult a healthcare professional as safety data are limited. - Store at ambient temperature: keep below 25 °C in the original packaging, protect from moisture and direct sunlight.

What does Paracetamol, Acetylsalicylic Acid, Caffeine interact with?

Nevralgio can interact with other medicines; awareness of key interactions helps prevent adverse outcomes.

Major Interactions (Avoid): - Anticoagulants (e.g., warfarin): increased bleeding risk. - Other NSAIDs or aspirin‑containing products: additive gastrointestinal toxicity. - Selective serotonin reuptake inhibitors (SSRIs): heightened bleeding tendency.

Moderate Interactions (Monitor Closely): - Diuretics: caffeine may reduce diuretic effectiveness. - Antihypertensives: caffeine can counteract blood‑pressure‑lowering effects. - Methotrexate: aspirin may decrease renal clearance, raising toxicity risk.

Frequently asked questions

What is Nevralgio used for?+
Nevralgio is an oral combination of paracetamol, acetylsalicylic acid and caffeine indicated for the relief of mild to moderate pain such as headache, dental or musculoskeletal discomfort, and for the reduction of fever in adults and adolescents.
How does the combination of paracetamol, aspirin and caffeine work?+
Paracetamol reduces central prostaglandin synthesis, aspirin irreversibly blocks peripheral COX‑1 and COX‑2 enzymes, and caffeine blocks adenosine receptors while stimulating the central nervous system. Together they provide synergistic analgesic and antipyretic effects, with caffeine enhancing the pain‑relieving action of the other two agents.
What is the usual dose of Nevralgio?+
The appropriate dose of Nevralgio is determined by a qualified prescriber based on the individual’s age, weight, medical condition and response to therapy. Patients should follow the dosing instructions provided on the prescription label and not exceed the recommended amount.
Is Nevralgio safe to use during pregnancy or breastfeeding?+
Safety data for Nevralgio in pregnancy and lactation are limited. Women who are pregnant, planning to become pregnant, or breastfeeding should consult their healthcare professional before using this product to weigh potential benefits against possible risks.
How do I order Nevralgio from GNH USA?+
To order Nevralgio, submit an enquiry on the product page at gnh-usa.com specifying the required quantity. GNH USA works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements) and necessary import documentation.
How does Nevralgio compare with other analgesics such as ibuprofen or single‑ingredient paracetamol?+
Nevralgio combines three agents, offering faster pain relief and enhanced fever reduction compared with single‑ingredient paracetamol. Unlike ibuprofen, it contains aspirin, which provides antiplatelet activity but may increase gastrointestinal risk. The caffeine component further augments analgesia, making Nevralgio useful when a stronger, multimodal effect is desired.
How should Nevralgio be stored and handled?+
Nevralgio tablets should be stored at ambient temperature, preferably below 25 °C, in their original blister pack or container. Keep the product away from moisture, direct sunlight and heat sources to maintain stability and potency throughout its shelf life.
How is Nevralgio administered?+
Nevralgio is taken orally with a full glass of water. It can be taken with or without food, although taking it with food may reduce the likelihood of gastric irritation. Swallow the tablet whole; do not crush or chew unless specifically instructed by a healthcare professional.
What are the most serious risks associated with Nevralgio?+
The most serious risks include gastrointestinal bleeding, especially in patients with ulcer disease or on anticoagulants; severe allergic reactions such as anaphylaxis; and liver toxicity if the product is taken in excess or combined with other hepatotoxic agents. Prompt medical attention is required if any of these symptoms occur.
Who should not use Nevralgio?+
Nevralgio should be avoided by individuals with known hypersensitivity to paracetamol, aspirin, caffeine or any excipients, children under 12 years of age, patients with active peptic ulcer disease, severe liver impairment, bleeding disorders, or those taking anticoagulant therapy unless directed by a physician.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Paracetamol, Acetylsalicylic Acid, Caffeine
Route
Oral Use
Manufacturer
Sc Sintofarm Sa
Origin
EU

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