Europe — EMA
Nevanac (Nepafenac)
GNH USA supplies Nevanac (nepafenac), a non‑steroidal anti‑inflammatory eye suspension for post‑operative inflammation and pain after cataract surgery.
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What is Nepafenac?
Nepafenac, the active ingredient in Nevanac, is a non‑steroidal anti‑inflammatory drug (NSAID) presented as an ophthalmic suspension for ocular use. It treats post‑operative inflammation and pain following cataract surgery in adults.
GNH USA supplies Nevanac as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, transplant centres, oncology centres, pharmacies and clinics worldwide.
What is Nepafenac used for?
Nevanac (nepafenac) is used to manage ocular inflammation and pain associated with surgical procedures.
- Post‑operative inflammation after cataract surgery: reduces inflammatory response in the operated eye. - Post‑operative pain after cataract surgery: alleviates discomfort and pain. - Anterior segment inflammation: helps control inflammation following ocular surgery.
What are the side effects of Nepafenac?
Common Side Effects: - Burning or stinging sensation on instillation. - Foreign body sensation. - Blurred vision. - Conjunctival hyperemia. - Itching or mild irritation. - Transient increased tear production.
Serious or Rare Side Effects: - Corneal ulceration or keratitis. - Significant increase in intra‑ocular pressure. - Severe allergic reactions such as angioedema. - Persistent eye pain. - Vision loss or sudden visual disturbances. - Endophthalmitis (infection inside the eye).
What precautions apply to Nepafenac?
Before prescribing Nevanac, clinicians should consider ocular health and patient history. - Assess for active ocular infection: avoid use if infection is present. - Known hypersensitivity: do not use in patients allergic to nepafenac or other NSAIDs. - Concomitant ocular NSAIDs: avoid simultaneous use to reduce toxicity risk. - Monitor intra‑ocular pressure in patients with glaucoma or ocular hypertension. - Store at room temperature: keep in the original container, protect from light and moisture.
What does Nepafenac interact with?
Nevanac may interact with other ophthalmic or systemic agents.
Major Interactions (Avoid): - Concurrent use with other ophthalmic NSAIDs: increased risk of corneal toxicity. - Simultaneous corticosteroid eye drops: may mask signs of infection. - Systemic NSAIDs: additive systemic exposure, though minimal with topical use.
Moderate Interactions (Monitor Closely): - Anticholinergic eye drops: possible reduction in therapeutic effect. - Beta‑blocker eye drops: monitor intra‑ocular pressure changes. - Preservative‑containing solutions: assess for additive irritation.
