Europe — EMA
Neurossen (Benfotiamine)
GNH USA supplies Neurossen (Benfotiamine), a Vitamin B1 derivative nutritional supplement for diabetic neuropathy and metabolic support.
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What is Benfotiamine?
Benfotiamine, the active ingredient in Neurossen, is a Vitamin B1 derivative presented as an oral supplement for oral use. It supports carbohydrate metabolism and is used as a nutritional supplement to help maintain healthy nerve function. GNH USA supplies Neurossen as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.
What is Benfotiamine used for?
Benfotiamine is a Vitamin B1 derivative that supports metabolic pathways and nerve health. - Diabetic peripheral neuropathy: supports nerve health and may reduce sensory symptoms. - Glucose metabolism support: helps maintain normal carbohydrate metabolism in the body. - Oxidative stress reduction: contributes to cellular antioxidant defenses, promoting overall metabolic balance.
What are the side effects of Benfotiamine?
Benfotiamine is generally well tolerated, but some users report adverse reactions.
Common Side Effects: - Nausea: mild stomach upset after ingestion. - Headache: transient mild headache. - Diarrhea: loose stools in a minority of users. - Skin rash: occasional mild erythema. - Dizziness: brief light‑headed sensation. - Fatigue: mild tiredness.
Serious or Rare Side Effects: - Anaphylaxis: severe allergic reaction requiring immediate medical attention. - Stevens‑Johnson syndrome: rare severe skin eruption. - Hepatic enzyme elevation: abnormal liver function tests. - Hematologic abnormalities: rare blood count changes. - Severe hypersensitivity: swelling of face or throat. - Acute pancreatitis: very rare abdominal pain with elevated enzymes.
What precautions apply to Benfotiamine?
When considering Benfotiamine, certain safety measures should be observed. - Pregnancy: safety not established; use only if clearly needed and under medical advice. - Breastfeeding: insufficient data; weigh benefits against potential risks. - Renal impairment: monitor because excretion may be reduced. - Concomitant medications: review all drugs to avoid unexpected interactions. - Storage: keep at ambient temperature: store in original container, protect from moisture and direct heat.
What does Benfotiamine interact with?
Benfotiamine may interact with other substances that affect thiamine status or metabolic pathways.
Major Interactions (Avoid): - High‑dose thiamine supplements: risk of excessive thiamine levels. - Alcohol dependence: may exacerbate thiamine deficiency.
Moderate Interactions (Monitor Closely): - Metformin: monitor glucose control as combined effect on carbohydrate metabolism. - Diuretics (e.g., thiazides): may increase urinary thiamine loss. - Anticonvulsants (e.g., phenobarbital, phenytoin): may accelerate thiamine metabolism. - Statins: observe for rare muscle complaints.



