Neurontin (Gabapentin)

Gabapentin, the active ingredient in Neurontin, is an anticonvulsant presented as an oral tablet for oral use. It is employed in the management of epilepsy, postherpetic neuralgia, other neuropathic pain conditions, and restless legs syndrome in adult patients.

GNH USA supplies Neurontin as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides reliable sourcing for global healthcare providers. Our distribution network ensures timely delivery across Europe, Asia, Africa and the Americas, supporting consistent patient access.

Gabapentin is used in several neurological and pain‑related conditions, acting on the central nervous system to alleviate symptoms.

Epilepsy: adjunctive therapy to reduce the frequency of partial seizures. Postherpetic neuralgia: relieves chronic nerve pain following shingles. Neuropathic pain: diminishes pain intensity in diabetic and other peripheral neuropathies. Restless legs syndrome: decreases uncomfortable sensations and urges to move the legs.

Common Side Effects: - Dizziness or light‑headedness. - Somnolence or fatigue. - Peripheral edema, especially in the lower extremities. - Weight gain or increased appetite.

Serious or Rare Side Effects: - Severe skin reactions, including Stevens‑Johnson syndrome. - Suicidal thoughts or behavior. - Anaphylactic or anaphylactoid reactions. - Blood dyscrasias such as agranulocytosis or thrombocytopenia.

Gabapentin requires careful consideration in certain patient groups and situations. - Renal impairment: dose adjustment may be necessary because the drug is excreted unchanged. - Pregnancy: safety has not been established; use only if clearly needed. - Elderly patients: increased risk of dizziness and falls; monitor closely. - Concomitant CNS depressants: may enhance sedation or respiratory depression. - Store at ambient temperature: keep in the original container, protect from moisture and direct sunlight.

Gabapentin can interact with several medications, altering efficacy or safety.

Major Interactions (Avoid): - Antacids containing aluminum or magnesium: may markedly reduce gabapentin absorption. - Opioids: combined use can increase risk of respiratory depression. - Alcohol: additive central nervous system depression.

Moderate Interactions (Monitor Closely): - Other CNS depressants (e.g., benzodiazepines, barbiturates): may enhance sedation. - Diuretics: can raise gabapentin plasma concentrations. - ACE inhibitors or angiotensin receptor blockers: monitor renal function and serum electrolytes.