Neuralgin Extra (Ibuprofen D,l-Lysinate)

Ibuprofen, the active ingredient in Neuralgin Extra, is a Nonsteroidal anti-inflammatory drug (NSAID) presented as an oral formulation for oral use. It is used to relieve pain, reduce fever, and lessen inflammation in adults and children when appropriate.

GNH USA supplies Neuralgin Extra as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Ibuprofen acts systemically to alleviate symptoms associated with inflammatory and febrile conditions. - Pain: provides analgesia for mild to moderate musculoskeletal and dental pain. - Fever: lowers elevated body temperature in febrile illnesses. - Inflammation: reduces swelling and stiffness in conditions such as arthritis or soft‑tissue injury.

Adverse reactions may range from mild to severe and should be monitored during therapy.

Common Side Effects: - Gastrointestinal upset: nausea, dyspepsia, or abdominal discomfort. - Headache or dizziness. - Mild skin rash or itching. - Elevated blood pressure in susceptible individuals.

Serious or Rare Side Effects: - Gastrointestinal bleeding, ulceration, or perforation. - Acute renal impairment or failure. - Severe hypersensitivity reactions, including anaphylaxis. - Hepatic dysfunction or elevated liver enzymes. - Hematologic abnormalities such as thrombocytopenia.

Before initiating therapy, consider patient‑specific risk factors and monitor appropriately. - Assess gastrointestinal risk: avoid in patients with active ulcers or a history of GI bleeding. - Evaluate renal function: use caution in those with chronic kidney disease. - Use the lowest effective dose for the shortest duration needed. - Avoid in individuals with known hypersensitivity to ibuprofen or other NSAIDs. - Monitor elderly patients closely for adverse events. - Store at ambient temperature: keep in the original pack, protect from moisture and direct sunlight.

Ibuprofen may alter the pharmacokinetics or pharmacodynamics of several co‑administered agents.

Major Interactions (Avoid): - Anticoagulants (e.g., warfarin): increased risk of bleeding. - Antiplatelet agents (e.g., clopidogrel): additive antithrombotic effect. - ACE inhibitors or ARBs: may reduce renal perfusion and precipitate renal failure.

Moderate Interactions (Monitor Closely): - Selective serotonin reuptake inhibitors (SSRIs): heightened bleeding tendency. - Corticosteroids: increased risk of gastrointestinal ulceration. - Methotrexate: reduced clearance leading to toxicity.