Neobrufen (Ibuprofen)

Ibuprofen, the active ingredient in Neobrufen, is a Nonsteroidal anti-inflammatory drug (NSAID) presented as an oral tablet for oral use. It treats mild to moderate pain, fever, and inflammatory conditions such as arthritis in adults and children when appropriate. GNH USA supplies Neobrufen as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Ibuprofen is an NSAID that reduces inflammation and pain by inhibiting cyclooxygenase enzymes.

Mild to moderate pain: provides analgesic relief for headaches, dental pain, and musculoskeletal discomfort. Fever: lowers elevated body temperature. Inflammatory conditions such as arthritis: decreases joint swelling and improves mobility.

Adverse reactions may occur with ibuprofen use and are categorized by frequency.

Common Side Effects: - Gastrointestinal upset (nausea, dyspepsia) - Headache - Dizziness - Mild rash or itching - Elevated liver enzymes - Mild increase in blood pressure

Serious or Rare Side Effects: - Gastrointestinal bleeding or ulceration - Severe renal impairment - Cardiovascular events such as myocardial infarction - Stevens‑Johnson syndrome or toxic epidermal necrolysis - Anaphylaxis or severe allergic reactions - Hepatotoxicity

Before using ibuprofen, consider the following safety measures.

Assess renal function: adjust use in patients with impaired kidney function. Monitor gastrointestinal risk: avoid in individuals with a history of ulcer or bleeding. Avoid concurrent anticoagulants: increased risk of hemorrhage. Use caution in pregnancy: limited data, consult a healthcare professional before use. Store at ambient temperature: keep in the original pack, protect from moisture.

Ibuprofen can interact with several medicines; awareness helps prevent adverse outcomes.

Major Interactions (Avoid): - Anticoagulants (e.g., warfarin): heightened bleeding risk. - Other NSAIDs: additive gastrointestinal toxicity. - Corticosteroids: increased ulcer risk.

Moderate Interactions (Monitor Closely): - ACE inhibitors or ARBs: may reduce renal function. - Diuretics: potential for renal impairment. - Lithium: possible increase in serum lithium levels.