Neo-Egmol (Ketoconazole)

Ketoconazole, the active ingredient in Neo-Egmol, is an imidazole antifungal presented as a topical formulation for skin use. It treats fungal infections such as tinea corporis, tinea cruris, seborrheic dermatitis, and pityriasis versicolor in both adults and children.

GNH USA supplies Neo-Egmol as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Ketoconazole is an imidazole antifungal that targets dermatophyte and yeast infections of the skin.

- Tinea corporis: reduces erythema, scaling and itching caused by dermatophyte infection. - Tinea cruris: alleviates rash and discomfort in the groin area. - Seborrheic dermatitis: controls flaking, redness and itching on scalp and face. - Pityriasis versicolor: clears discolored patches caused by Malassezia species.

Common Side Effects: - Skin irritation: mild burning or stinging at the application site. - Itching: transient pruritus during early treatment. - Redness: localized erythema. - Dryness: temporary loss of skin moisture. - Scaling: mild flaking of the treated area. - Sensation of tightness: brief feeling of tight skin.

Serious or Rare Side Effects: - Allergic contact dermatitis: severe rash, swelling or blistering. - Stevens‑Johnson syndrome: rare, life‑threatening skin reaction. - Photosensitivity: increased susceptibility to sunburn. - Systemic absorption leading to hepatic dysfunction: very uncommon but reported with extensive use.

Before using Neo‑Egmol, consider the following precautions: - Avoid application on broken or inflamed skin: may increase irritation. - Do not apply near eyes or mucous membranes: risk of severe irritation. - Use only for the indicated fungal conditions: off‑label use is not recommended. - Monitor for signs of allergic reaction: discontinue if severe rash develops. - Keep out of reach of children: accidental ingestion can cause systemic effects. - Store at room temperature: keep in the original container, protect from moisture and light.

Ketoconazole can interact with other agents when applied to the skin.

Major Interactions (Avoid): - Systemic azole antifungals (e.g., itraconazole): may increase systemic exposure. - Oral corticosteroids: combined use may raise risk of adrenal suppression. - Warfarin: topical ketoconazole may potentiate anticoagulant effect.

Moderate Interactions (Monitor Closely): - Topical retinoids: may enhance skin irritation. - Sunscreen agents: potential for increased photosensitivity. - Other antifungal creams: overlapping toxicity should be assessed.