Nenoxin (Mometasone Furoate Monohydrate)

Mometasone furoate monohydrate, the active ingredient in Nenoxin, is a glucocorticoid presented as a nasal spray for nasal use. It treats allergic rhinitis, including seasonal and perennial forms, in adults and children by reducing nasal inflammation, congestion, sneezing, itching and rhinorrhea.

GNH USA supplies Nenoxin as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The product complies with EU regulatory standards and is distributed to global markets.

Nenoxin (mometasone furoate monohydrate) is a nasal corticosteroid that reduces inflammation in the nasal mucosa.

- Allergic rhinitis: provides relief of nasal congestion, sneezing, itching and runny nose. - Seasonal allergic rhinitis: controls symptoms triggered by pollen or other seasonal allergens. - Perennial allergic rhinitis: maintains symptom control throughout the year for continuous allergen exposure.

Nasally administered mometasone furoate may be associated with local and systemic adverse reactions.

Common Side Effects: - Nasal irritation or burning sensation. - Epistaxis (nosebleeds). - Headache. - Throat irritation or dryness. - Cough. - Altered taste or bitter taste.

Serious or Rare Side Effects: - Nasal septal perforation. - Severe allergic reaction (anaphylaxis). - Adrenal suppression with prolonged use. - Increased intra‑ocular pressure or glaucoma. - Fungal infection of the nasal passages. - Vision changes.

When using Nenoxin, several precautions should be observed to ensure safety and effectiveness.

- Use as prescribed: follow the clinician’s instructions for frequency and duration. - Avoid prolonged continuous use without medical review. - Monitor for signs of nasal infection or worsening symptoms. - Caution in patients with glaucoma, cataracts, or uncontrolled diabetes. - Use with care in children under two years of age unless directed. - Pregnancy and lactation: safety not established; discuss with healthcare provider. - Store at room temperature: keep in the original container, protect from moisture and direct sunlight.

Mometasone furoate nasal spray can interact with other medicines, affecting its safety or efficacy.

Major Interactions (Avoid): - Strong CYP3A4 inhibitors (e.g., ketoconazole, itraconazole, ritonavir) may increase systemic exposure. - Concurrent systemic corticosteroids can enhance glucocorticoid‑related adverse effects. - Live vaccines: immunosuppression may reduce vaccine effectiveness.

Moderate Interactions (Monitor Closely): - Antifungal agents (e.g., fluconazole) may modestly raise mometasone levels. - Nasal decongestants (e.g., oxymetazoline) may increase local irritation. - Antihistamines may enhance sedative effects when combined with other CNS depressants.