GNH USA

Europe — EMA

Neisvac-C

GNH USA supplies Neisvac-C (Tetanus toxoid, algeldrate, N. meningitidis group C polysaccharide), a vaccine for prevention of tetanus and meningococcal group

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What is Tetanus Toxoid, Algeldrate, N. Meningitidis Group C (Strain C11) Polysaccharide (De-O-Acetylated)?

Tetanus toxoid, algeldrate, Neisseria meningitidis group C (de-O-acetylated) polysaccharide, the active ingredient in Neisvac-C, is a vaccine presented as a lyophilized powder for reconstitution for intramuscular use. It provides active immunity against tetanus and Neisseria meningitidis group C infections in individuals requiring prophylactic immunization.

GNH USA supplies Neisvac-C as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

What is Tetanus Toxoid, Algeldrate, N. Meningitidis Group C (Strain C11) Polysaccharide (De-O-Acetylated) used for?

Neisvac-C is indicated for immunization against bacterial toxins and encapsulated organisms. - Tetanus: induces protective antibodies that neutralize tetanus toxin and prevent disease. - Neisseria meningitidis group C infection: stimulates immunity against the group C polysaccharide to reduce risk of invasive meningococcal disease. - Combined tetanus‑meningococcal prophylaxis: offers simultaneous protection against both tetanus and meningococcal group C in a single injection.

What are the side effects of Tetanus Toxoid, Algeldrate, N. Meningitidis Group C (Strain C11) Polysaccharide (De-O-Acetylated)?

Common Side Effects: - Injection site pain: mild to moderate discomfort at the injection site. - Redness or swelling: localized erythema or edema that resolves within a few days. - Fever: transient low‑grade temperature elevation. - Headache or fatigue: general malaise following vaccination.

Serious or Rare Side Effects: - Anaphylaxis: severe allergic reaction requiring immediate medical attention. - Guillain‑Barré syndrome: rare neurologic disorder characterized by muscle weakness. - Seizures: uncommon neurologic event post‑vaccination. - Severe hypotension or shock: rare circulatory compromise needing urgent care.

What precautions apply to Tetanus Toxoid, Algeldrate, N. Meningitidis Group C (Strain C11) Polysaccharide (De-O-Acetylated)?

Precautions should be observed before administering Neisvac-C. - Allergy assessment: avoid in persons with known hypersensitivity to any component, especially tetanus toxoid or algeldrate. - Pregnancy: use only if the expected benefit outweighs potential risk; consult a healthcare professional. - Immunocompromised patients: vaccine may be less immunogenic; monitor serologic response. - Concurrent immunizations: may be given with other vaccines at separate anatomical sites. - Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.

What does Tetanus Toxoid, Algeldrate, N. Meningitidis Group C (Strain C11) Polysaccharide (De-O-Acetylated) interact with?

Potential drug interactions should be considered. Major Interactions (Avoid): - Live vaccines: avoid simultaneous administration as immune interference may occur. - Immunoglobulin therapy: may reduce vaccine efficacy if given within two weeks of vaccination. - Blood products: may interfere with antibody development if administered within four weeks. Moderate Interactions (Monitor Closely): - Antipyretics: may mask post‑vaccination fever; use as needed. - Immunosuppressive drugs: may diminish immune response; consider monitoring antibody titres.

Frequently asked questions

What is Neisvac-C used for?+
Neisvac-C is a combination vaccine used to prevent tetanus and invasive disease caused by Neisseria meningitidis group C. It is administered as a single intramuscular injection to provide active immunity against both bacterial agents in individuals who need prophylactic protection.
How does the tetanus toxoid and meningococcal polysaccharide work in Neisvac-C?+
The tetanus toxoid component stimulates a T‑cell‑dependent immune response that generates neutralizing antibodies against tetanus toxin. The de‑O‑acetylated group C polysaccharide induces a T‑cell‑independent response, producing antibodies that target the meningococcal capsule. Algeldrate acts as an adjuvant to enhance the overall immune reaction.
What is the usual dose of Neisvac-C?+
The dosage and schedule of Neisvac-C are determined by the prescribing healthcare professional based on age, immunization history, and local guidelines. The vaccine is supplied as a lyophilized powder that is reconstituted and given as a single intramuscular injection.
Is Neisvac-C safe to use during pregnancy or breastfeeding?+
Safety data for Neisvac-C in pregnancy are limited. It should be administered only if the expected benefit to the mother outweighs any potential risk to the fetus, and the decision should be made by a qualified health professional. Breastfeeding is not a contraindication, but consultation with a clinician is advised.
How do I order Neisvac-C from GNH USA?+
To place an order, submit an enquiry on the product page at gnh-usa.com specifying the required quantity. GNH USA works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, cold‑chain shipping details and any necessary import documentation.
How does Neisvac-C compare with other tetanus‑meningococcal vaccines?+
Neisvac-C combines tetanus toxoid with a de‑O‑acetylated group C polysaccharide, whereas some alternatives may include additional meningococcal serogroups or use conjugated polysaccharides. The choice depends on regional disease prevalence, immunization schedules, and regulatory approvals. Both provide protection against tetanus, but Neisvac-C focuses specifically on group C meningococcal disease.
What are the storage and handling requirements for Neisvac-C?+
Neisvac-C must be stored refrigerated at 2‑8 °C. It should be kept in its original packaging, protected from light, and must not be frozen or shaken. After reconstitution, the vaccine should be used promptly according to the manufacturer’s instructions.
How is Neisvac-C administered?+
Neisvac-C is supplied as a lyophilized powder that is reconstituted with a sterile diluent. The reconstituted solution is injected intramuscularly, typically into the deltoid muscle of adults or the anterolateral thigh of infants and young children, following aseptic technique.
What are the most serious risks associated with Neisvac-C?+
The most serious adverse events reported with Neisvac-C include severe allergic reactions such as anaphylaxis, Guillain‑Barré syndrome, and rare neurologic complications like seizures. Immediate medical attention is required if any signs of a severe reaction occur after vaccination.
Who should not receive Neisvac-C?+
Neisvac-C should not be given to individuals with a known hypersensitivity to tetanus toxoid, algeldrate, or the meningococcal group C polysaccharide. It is also contraindicated in persons who have experienced a severe allergic reaction to a previous dose of the same vaccine.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Tetanus Toxoid, Algeldrate, N. Meningitidis Group C (Strain C11) Polysaccharide (De-O-Acetylated)
Route
Intramuscular Use
Manufacturer
Pfizer Healthcare Ireland Unlimited Company
Origin
EU

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