Nebivolol/Hydrochlorothiazide Teva (Hydrochlorothiazide, Nebivolol)

Nebivolol, the active ingredient in Nebivolol/Hydrochlorothiazide Teva, is a beta‑blocker presented as a combination tablet for oral use. It treats hypertension, often in adults who need both heart‑rate control and diuretic therapy.

GNH USA supplies Nebivolol/Hydrochlorothiazide Teva as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals and pharmacies worldwide.

Nebivolol/Hydrochlorothiazide is indicated for hypertension, a condition characterized by elevated arterial pressure. - Essential hypertension: lowers systolic and diastolic blood pressure through combined beta‑blockade and diuresis. - Stage 2 hypertension: provides stronger blood‑pressure reduction when monotherapy is insufficient. - Hypertension with fluid retention: addresses both vascular resistance and excess plasma volume.

Common Side Effects: - Dizziness: transient light‑headedness, especially after the first doses. - Headache: mild to moderate intensity, often resolves with continued therapy. - Fatigue: feeling of tiredness or reduced energy. - Increased urination: due to the diuretic component. - Electrolyte imbalance (mild): slight changes in potassium or sodium levels. - Nausea: occasional stomach upset.

Serious or Rare Side Effects: - Severe hypotension: marked drop in blood pressure causing fainting. - Hyponatremia or hypokalemia: significant electrolyte disturbances requiring monitoring. - Gout flare: increased uric acid levels may precipitate attacks. - Acute renal impairment: reduced kidney function, especially in patients with pre‑existing renal disease. - Allergic reactions: rash, itching, or swelling of the face and throat. - Pancreatitis: rare inflammation of the pancreas presenting with abdominal pain.

Before initiating therapy, consider the following precautions: - Renal function: assess creatinine clearance and adjust if necessary. - Electrolytes: monitor serum potassium and sodium regularly. - Diabetes mellitus: watch for altered glucose control. - Asthma or COPD: beta‑blockade may exacerbate bronchospasm. - Pregnancy: avoid unless the potential benefit justifies the risk. - Store at ambient temperature: keep in the original container, protect from moisture and direct sunlight.

Nebivolol/Hydrochlorothiazide may interact with several drug classes. Major Interactions (Avoid): - Non‑selective beta‑blockers: additive bradycardia and AV‑block. - Potassium‑sparing diuretics: risk of hyperkalemia. - Lithium: increased lithium toxicity. - NSAIDs: may blunt diuretic efficacy and worsen renal function. - Antidiabetic agents: may mask hypoglycaemia symptoms. Moderate Interactions (Monitor Closely): - ACE inhibitors or ARBs: enhanced hypotensive effect. - Calcium channel blockers: additive blood‑pressure reduction. - SSRIs or other antidepressants: potential for increased bradycardia.