GNH USA

Europe — EMA

Nealgin (Paracetamol, Propyphenazone, Caffeine)

GNH USA supplies Nealgin (Paracetamol / Propyphenazone / Caffeine), an analgesic, antipyretic and NSAID combo for moderate pain and fever. Request a quote.

Paracetamol, Propyphenazone, Caffeine

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What is Paracetamol, Propyphenazone, Caffeine?

Paracetamol/Propyphenazone/Caffeine, the active ingredients in Nealgin, are an analgesic, antipyretic and non‑steroidal anti‑inflammatory combination presented as an oral tablet for oral use. It relieves mild to moderate pain, reduces fever and eases headache in adult patients.

GNH USA supplies Nealgin as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

What is Paracetamol, Propyphenazone, Caffeine used for?

Nealgin combines analgesic and antipyretic actions to manage common pain‑related conditions.

- Mild to moderate pain: provides rapid relief of muscle, dental or postoperative discomfort. - Fever: lowers elevated body temperature associated with infections or inflammatory states. - Headache: alleviates tension‑type and mild migraine episodes.

What are the side effects of Paracetamol, Propyphenazone, Caffeine?

Nealgin may cause a range of adverse reactions, most of which are mild and reversible.

Common Side Effects: - Nausea or upset stomach. - Dizziness or light‑headedness. - Insomnia or restlessness. - Mild headache. - Skin rash or itching. - Increased heart rate.

Serious or Rare Side Effects: - Severe allergic reactions (anaphylaxis, angioedema). - Hepatotoxicity, especially with excessive paracetamol intake. - Blood dyscrasias such as agranulocytosis. - Gastrointestinal bleeding or ulceration. - Stevens‑Johnson syndrome or toxic epidermal necrolysis. - Cardiovascular events linked to caffeine excess.

What precautions apply to Paracetamol, Propyphenazone, Caffeine?

Before using Nealgin, consider the following safety measures.

- Liver function assessment: avoid in patients with severe hepatic impairment. - Hypersensitivity check: discontinue if allergic reactions occur. - Hypertension monitoring: caffeine may raise blood pressure. - Pregnancy and lactation: use only if benefits outweigh potential risks. - Alcohol avoidance: concurrent alcohol increases liver toxicity risk. - Store at room temperature: keep in the original pack, protect from moisture.

What does Paracetamol, Propyphenazone, Caffeine interact with?

Nealgin can interact with several medicines; awareness helps prevent complications.

Major Interactions (Avoid): - Other NSAIDs (e.g., ibuprofen): heightened risk of gastrointestinal bleeding. - Anticoagulants (e.g., warfarin): increased bleeding tendency. - Alcohol with paracetamol: potential for severe liver injury.

Moderate Interactions (Monitor Closely): - CYP1A2 inhibitors (e.g., fluvoxamine): may raise caffeine plasma levels. - Diuretics: can amplify propyphenazone‑related toxicity. - Central depressants (e.g., opioids, benzodiazepines): additive sedation or respiratory depression.

Frequently asked questions

What is Nealgin used for?+
Nealgin is a fixed‑dose combination of paracetamol, propyphenazone and caffeine indicated for the relief of mild to moderate pain, reduction of fever, and treatment of common headaches in adult patients.
How does the combination of paracetamol, propyphenazone and caffeine work?+
Paracetamol reduces pain and fever by centrally inhibiting COX enzymes, propyphenazone blocks peripheral prostaglandin synthesis to lessen inflammation, and caffeine antagonises adenosine receptors, enhancing analgesic potency and counteracting drowsiness.
What is the usual dose of Nealgin?+
The dosage of Nealgin is determined by the prescribing healthcare professional based on the patient’s condition, age, weight and clinical response. Patients should follow the prescriber’s instructions and not exceed the recommended amount.
Is Nealgin safe to use during pregnancy or breastfeeding?+
Safety data for Nealgin in pregnancy and lactation are limited. It should only be used if the potential benefit justifies any possible risk to the fetus or infant, and the decision must be made by a qualified healthcare provider.
How do I order Nealgin from GNH USA?+
To request Nealgin, submit an enquiry on the product page at gnh-usa.com, specifying the required quantity. GNH USA works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.
How does Nealgin compare with other pain‑relief options?+
Nealgin combines an antipyretic (paracetamol), an NSAID (propyphenazone) and a stimulant (caffeine), offering synergistic pain relief and fever reduction. Compared with single‑ingredient products, it may provide faster onset and enhanced efficacy, but it also carries the combined safety profile of all three components.
What are the recommended storage conditions for Nealgin?+
Nealgin should be stored at room temperature, below 25 °C, in its original packaging. Keep the product away from moisture and direct sunlight to maintain stability and potency.
How is Nealgin administered?+
Nealgin is taken orally, usually with a glass of water. It can be taken with or without food, but patients should follow the specific instructions given by their prescriber.
What are the most serious risks associated with Nealgin?+
Serious risks include severe allergic reactions, liver injury from excessive paracetamol, gastrointestinal bleeding from the NSAID component, and rare blood disorders. Patients should seek immediate medical attention if they experience symptoms such as rash, jaundice, vomiting blood or unexplained bruising.
Who should not use Nealgin?+
Nealgin is contraindicated in individuals with known hypersensitivity to any of its ingredients, severe liver disease, active peptic ulcer disease, uncontrolled hypertension, or those who are currently taking other NSAIDs or anticoagulants without medical supervision.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.
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Product details

Drug
Paracetamol, Propyphenazone, Caffeine
Route
Oral Use
Manufacturer
Stirolbiofarm Baltikum Sia
Origin
EU

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