Navela (Levonorgestrel)

Levonorgestrel, the active ingredient in Navela, is a progestogen presented as a tablet for oral use. It is employed as emergency contraception to reduce the risk of pregnancy after unprotected sexual contact or contraceptive failure in women of reproductive age.

GNH USA supplies Navela as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides regulatory documentation to support safe distribution across global markets. Clients benefit from reliable supply chains and responsive technical support.

Levonorgestrel is a synthetic progestogen used in the hormonal pathway of emergency contraception.

- Unprotected intercourse: Reduces the chance of pregnancy when taken within 72 hours after the event. - Contraceptive failure: Provides a backup method after missed oral contraceptive pills or condom breakage. - Delayed ovulation: Inhibits ovulation to prevent fertilisation of the egg.

Levonorgestrel is generally well tolerated, but some users experience adverse reactions.

Common Side Effects: - Nausea: Mild to moderate upset stomach. - Abdominal pain: Cramping or discomfort in the lower abdomen. - Fatigue: Temporary feeling of tiredness. - Headache: Mild to moderate head pain. - Dizziness: Light‑headed sensation. - Menstrual changes: Spotting or altered timing of the next period.

Serious or Rare Side Effects: - Allergic reaction: Rash, itching, swelling, or difficulty breathing. - Severe abdominal pain: Persistent or worsening pain may indicate complications. - Vomiting blood or severe gastrointestinal bleeding. - Chest pain or palpitations. - Severe headache or visual disturbances. - Liver dysfunction: Unusual jaundice or elevated liver enzymes.

Before using Navela, consider the following safety measures.

- Timing of intake: Take as soon as possible after unprotected intercourse, ideally within 72 hours. - Contraindications: Do not use if there is a known hypersensitivity to levonorgestrel or any tablet excipients. - Medical conditions: Use with caution in women with active liver disease or uncontrolled epilepsy. - Pregnancy status: Not intended for use if the user is already pregnant; confirm pregnancy status when possible. - Drug interactions: Review concurrent medications that may reduce efficacy, such as enzyme‑inducing agents. - Store at ambient temperature: Keep below 25 °C, in the original packaging, protected from moisture and light.

Levonorgestrel may interact with several medicines that affect its effectiveness.

Major Interactions (Avoid): - Combined hormonal contraceptives: May reduce the effectiveness of emergency contraception. - Antiepileptic drugs (e.g., carbamazepine, phenytoin): Can lower levonorgestrel plasma levels. - Rifampin and other strong enzyme inducers: Decrease efficacy of the tablet.

Moderate Interactions (Monitor Closely): - Antifungal azoles (e.g., ketoconazole): May increase levonorgestrel exposure, requiring observation. - St. John’s wort: Potential modest reduction in effectiveness; monitor timing of intake.