Nasotasone (Mometasone Furoate)

Mometasone furoate, the active ingredient in Nasotasone, is a corticosteroid presented as a nasal spray for endosinusial use. It reduces inflammation in the nasal passages and is indicated for allergic rhinitis and nasal polyps in adults and children.

GNH USA supplies Nasotasone as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Mometasone furoate nasal spray is used to treat inflammatory conditions of the nasal passages.

- Allergic rhinitis: alleviates nasal congestion, sneezing, itching and rhinorrhea caused by seasonal or perennial allergens. - Nasal polyps: helps shrink polyps and improves nasal airflow, reducing obstruction. - Seasonal allergic rhinitis: provides symptom relief during peak pollen periods.

Common Side Effects: - Nasal irritation or burning sensation. - Headache. - Epistaxis (nosebleeds). - Sore throat. - Cough. - Altered taste or unpleasant taste.

Serious or Rare Side Effects: - Nasal septal perforation. - Severe or persistent epistaxis. - Adrenal suppression with prolonged high‑dose use. - Vision changes such as cataracts or glaucoma. - Fungal infection of the nasal mucosa. - Systemic corticosteroid effects (rare).

Before using Nasotasone, consider the following precautions: - Assess for active nasal infection: avoid use if bacterial or fungal sinusitis is present. - Evaluate for recent nasal surgery or trauma: delay use until healing is complete. - Monitor for signs of adrenal insufficiency: especially with long‑term high‑dose therapy. - Caution in patients with glaucoma or cataracts: inform the prescriber of ocular history. - Avoid abrupt discontinuation after prolonged therapy: taper under medical guidance. - Store at room temperature: keep in the original container, protect from moisture and heat.

Mometasone furoate nasal spray may interact with other medications as follows:

Major Interactions (Avoid): - Systemic corticosteroids: concurrent use can increase risk of systemic steroid effects. - Strong CYP3A4 inhibitors (e.g., ketoconazole, ritonavir): may elevate systemic exposure if large amounts are absorbed.

Moderate Interactions (Monitor Closely): - Antifungal agents (e.g., itraconazole): monitor for increased local steroid activity. - Nasal decongestants: may mask local irritation, requiring careful assessment. - Immunosuppressants: watch for heightened risk of local infections.