Nasonex (Mometasone Furoate)

Mometasone furoate, the active ingredient in Nasonex, is a corticosteroid presented as a nasal spray for nasal use. It treats allergic rhinitis and nasal polyps by reducing inflammation in the nasal passages.

GNH USA supplies Nasonex as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Nasonex (mometasone furoate) is a nasal corticosteroid used to manage inflammatory conditions of the nasal mucosa. - Allergic rhinitis: alleviates nasal congestion, sneezing and itching by reducing mucosal inflammation. - Nasal polyps: shrinks polyp size and improves airflow through anti‑inflammatory action. - Seasonal allergic rhinitis: provides symptom relief during pollen seasons by controlling inflammatory response.

Nasonex may cause local and systemic adverse reactions, most of which are mild and reversible.

Common Side Effects: - Nasal irritation: mild burning or stinging. - Headache: transient headache. - Epistaxis: occasional nosebleeds.

Serious or Rare Side Effects: - Nasal septal perforation: rare tissue damage. - Vision changes: blurred vision or cataract formation. - Suppression of hypothalamic‑pituitary‑adrenal axis: systemic corticosteroid effect.

Before prescribing Nasonex, clinicians should consider several precautionary measures to ensure safe use. - Assess infection: avoid use in patients with active nasal or sinus infections. - Monitor intraocular pressure: patients with glaucoma risk should be evaluated. - Evaluate for cataracts: long‑term use may increase cataract risk. - Consider systemic corticosteroid exposure: caution in patients receiving other steroids. - Pregnancy and lactation: use only if benefit outweighs potential risk. - Store at ambient temperature: keep below 25°C in original container, protect from moisture.

Mometasone furoate can interact with other medicines that affect corticosteroid activity or nasal absorption.

Major Interactions (Avoid): - Systemic CYP3A4 inhibitors: may increase systemic exposure. - Strong nasal decongestants: can mask local irritation, leading to overuse.

Moderate Interactions (Monitor Closely): - Other inhaled or intranasal steroids: additive corticosteroid effects. - Antifungal azoles (ketoconazole, itraconazole): may raise plasma levels. - Ritonavir or other protease inhibitors: potential increase in corticosteroid activity.