GNH USA

Europe — EMA

Nasonal 1 Mg/Ml (Xylometazoline Hydrochloride)

GNH USA supplies Nasonal 1 Mg/Ml (Xylometazoline Hydrochloride), a nasal decongestant for congestion due to common cold, sinusitis and allergic rhinitis.

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What is Xylometazoline Hydrochloride?

Xylometazoline Hydrochloride, the active ingredient in Nasonal 1 Mg/Ml, is an imidazoline derivative (nasal decongestant) presented as a 1 mg/mL nasal solution for nasal use. It relieves nasal congestion associated with the common cold, sinusitis, and allergic rhinitis in adults and children.

GNH USA supplies Nasonal 1 Mg/Ml as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies, clinics and other healthcare providers worldwide.

What is Xylometazoline Hydrochloride used for?

Xylometazoline Hydrochloride works as a topical nasal decongestant to reduce swelling of the nasal mucosa in several common conditions.

- Common cold nasal congestion: reduces swelling and improves airflow. - Sinusitis‑related congestion: alleviates mucosal edema for better sinus drainage. - Allergic rhinitis: decreases nasal obstruction caused by allergic inflammation.

What are the side effects of Xylometazoline Hydrochloride?

Nasal decongestants may cause local and systemic reactions, most of which are mild and reversible.

Common Side Effects: - Nasal irritation or burning sensation. - Dryness of the nasal mucosa. - Sneezing or mild itching. - Headache. - Altered taste or bitter after‑taste. - Transient epistaxis (nosebleed).

Serious or Rare Side Effects: - Severe hypertension or hypertensive crisis. - Cardiac arrhythmias. - Nasal septum perforation with prolonged misuse. - Anaphylactic reaction. - Rebound congestion (rhinitis medicamentosa) after extended use. - Vision disturbances (rare).

What precautions apply to Xylometazoline Hydrochloride?

Before using Xylometazoline Hydrochloride, consider the following safety measures.

- Pregnancy: safety not established; consult a healthcare professional. - Children under 2 years: avoid unless specifically directed by a clinician. - Cardiovascular disease: use with caution due to possible blood pressure effects. - Concomitant sympathomimetic drugs: monitor for additive cardiovascular stimulation. - Duration of use: limit to no more than three consecutive days to prevent rebound congestion. - Store at room temperature: keep in the original container, protect from moisture and heat.

What does Xylometazoline Hydrochloride interact with?

Xylometazoline Hydrochloride can interact with other medications that affect the cardiovascular or sympathetic systems.

Major Interactions (Avoid): - Monoamine oxidase inhibitors (MAOIs): risk of hypertensive crisis. - Other nasal decongestants: additive vasoconstriction may increase adverse effects. - Systemic sympathomimetics (e.g., pseudoephedrine): heightened cardiovascular stimulation.

Moderate Interactions (Monitor Closely): - Antihypertensive agents: possible reduction in blood‑pressure‑lowering effect. - Beta‑blockers: may blunt compensatory cardiovascular responses. - Tricyclic antidepressants: potential additive sympathomimetic activity.

Frequently asked questions

What is Nasonal 1 Mg/Ml used for?+
Nasonal 1 Mg/Ml contains Xylometazoline Hydrochloride, a nasal decongestant used to relieve nasal blockage caused by the common cold, sinusitis, and allergic rhinitis. It works locally in the nasal passages to reduce swelling and improve airflow.
How does Xylometazoline Hydrochloride work?+
Xylometazoline Hydrochloride is a selective alpha‑adrenergic agonist. By stimulating alpha‑1 receptors on the blood vessels of the nasal mucosa, it causes vasoconstriction, which reduces blood flow, edema, and congestion, allowing the nasal passages to open.
What is the usual dose of Nasonal 1 Mg/Ml?+
The appropriate dose of Nasonal 1 Mg/Ml is determined by a qualified prescriber based on the patient’s age, condition, and response. Typically, a few sprays per nostril are used, but exact instructions should follow the healthcare professional’s recommendation.
Is Nasonal 1 Mg/Ml safe during pregnancy or breastfeeding?+
Safety data for Xylometazoline Hydrochloride in pregnancy and lactation are limited. Women who are pregnant or breastfeeding should discuss potential risks and benefits with their healthcare provider before using the product.
How do I order Nasonal 1 Mg/Ml from GNH USA?+
To order, submit an enquiry on the product page at gnh-usa.com specifying the required quantity. GNH USA works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details, and any necessary import documentation.
How does Nasonal compare with other nasal decongestants?+
Nasonal’s active ingredient, Xylometazoline Hydrochloride, belongs to the imidazoline class, offering rapid vasoconstriction similar to phenylephrine‑based sprays. Compared with oxymetazoline, it has a comparable onset but may have a slightly shorter duration, making it suitable for short‑term relief.
What are the storage and handling requirements for Nasonal 1 Mg/Ml?+
Store Nasonal 1 Mg/Ml at room temperature, below 25 °C, in its original packaging. Protect the container from moisture, direct sunlight, and extreme heat to maintain product stability.
How is Nasonal 1 Mg/Ml administered?+
Nasonal is a nasal solution intended for intranasal use. The prescribed number of sprays is applied into each nostril, usually while the head is upright. The patient should avoid blowing the nose immediately after administration to allow optimal absorption.
What are the most serious risks associated with Nasonal 1 Mg/Ml?+
Serious risks, though rare, include severe hypertension, cardiac arrhythmias, nasal septum perforation from prolonged misuse, and anaphylactic reactions. Users should discontinue the product and seek medical attention if they experience symptoms such as a rapid rise in blood pressure, chest pain, or severe allergic signs.
Who should not use Nasonal 1 Mg/Ml?+
Individuals with known hypersensitivity to Xylometazoline Hydrochloride or any component of the formulation should avoid use. Patients with uncontrolled hypertension, severe cardiovascular disease, or those taking MAO inhibitors should consult a healthcare professional before using the product.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Xylometazoline Hydrochloride
Route
Nasal Use
Manufacturer
Jadran-Galenski Laboratorij D.D.
Origin
EU

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