GNH USA

Europe — EMA

Nasomaris 0,5 Mg/Ml (Xylometazoline Hydrochloride)

GNH USA supplies Nasomaris 0.5 mg/mL (Xylometazoline Hydrochloride), a nasal decongestant for congestion from colds, sinusitis and rhinitis. Request a quote.

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What is Xylometazoline Hydrochloride?

Xylometazoline Hydrochloride, the active ingredient in Nasomaris 0.5 mg/mL, is an imidazoline nasal decongestant presented as a 0.5 mg/mL solution for nasal use. It relieves nasal congestion caused by the common cold, sinusitis, and allergic rhinitis in adults and children.

GNH USA supplies Nasomaris 0.5 mg/mL as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies, clinics and research institutions worldwide, adhering to stringent quality standards and regulatory requirements. The company provides reliable logistics, batch traceability, and after‑sales support to ensure product integrity across global markets.

What is Xylometazoline Hydrochloride used for?

Xylometazoline Hydrochloride acts as a topical nasal decongestant to reduce swelling of the nasal mucosa.

- Common cold nasal congestion: decreases mucosal edema and improves airflow during viral upper respiratory infections. - Sinusitis-related congestion: alleviates blockage of sinus ostia by shrinking swollen nasal tissues. - Allergic rhinitis: reduces nasal swelling and congestion triggered by allergen exposure.

What are the side effects of Xylometazoline Hydrochloride?

Xylometazoline Hydrochloride may cause local and systemic adverse reactions, most of which are mild and transient.

Common Side Effects: - Burning or stinging in the nose: a transient sensation that usually resolves within minutes after application. - Mild headache: occasional tension‑type headache that does not require medical intervention. - Nasal dryness or crusting: reduced moisture leading to a dry, crusty lining of the nasal passages. - Sneezing: a brief reflexive sneeze that may occur immediately following spray.

Serious or Rare Side Effects: - Elevated blood pressure: systemic vasoconstriction can raise arterial pressure, especially with overuse. - Severe nasal irritation or ulceration: persistent pain, bleeding, or ulcer formation in the nasal mucosa. - Allergic reactions: rash, itching, swelling of the face or throat, and in rare cases anaphylaxis.

What precautions apply to Xylometazoline Hydrochloride?

When using Nasomaris, consider the following precautions to ensure safe and effective use.

- Age restriction: not recommended for children under 2 years without medical advice. - Duration of use: limit to three consecutive days to avoid rebound congestion. - Pre‑existing hypertension: use with caution and monitor blood pressure. - Concurrent nasal surgery or trauma: avoid use until healing is complete. - Allergic history: discontinue if signs of hypersensitivity appear. - Store at room temperature: keep below 25 °C, in the original container, protected from moisture and direct sunlight.

What does Xylometazoline Hydrochloride interact with?

Xylometazoline Hydrochloride can interact with certain medications and substances.

Major Interactions (Avoid): - Monoamine oxidase inhibitors (MAOIs): may potentiate hypertensive effects. - Sympathomimetic drugs (e.g., pseudoephedrine): combined vasoconstriction can raise blood pressure. - Nasal antihistamine sprays: concurrent use may increase local irritation.

Moderate Interactions (Monitor Closely): - Beta‑blockers: monitor for additive cardiovascular effects. - Antihypertensive agents: may reduce efficacy of blood pressure control. - Alcohol: can enhance dizziness or headache.

Frequently asked questions

What is Nasomaris used for?+
Nasomaris contains Xylometazoline Hydrochloride and is indicated for the temporary relief of nasal congestion associated with the common cold, sinusitis, and allergic rhinitis. It works by narrowing blood vessels in the nasal passages, reducing swelling and improving airflow.
How does Xylometazoline Hydrochloride work?+
Xylometazoline Hydrochloride is a selective alpha‑adrenergic agonist. By stimulating α1‑ and α2‑receptors on nasal blood‑vessel smooth muscle, it causes vasoconstriction, which lowers blood flow and vascular permeability, thereby decreasing mucosal edema and opening the nasal airway.
What is the usual dose of Nasomaris?+
The appropriate dose of Nasomaris is determined by a qualified healthcare professional. Typically, a few sprays per nostril are administered, but the exact number of sprays, frequency, and duration should follow the prescriber's instructions and the product label.
Is Nasomaris safe during pregnancy or breastfeeding?+
Safety data for Xylometazoline Hydrochloride in pregnancy and lactation are limited. Women who are pregnant, planning to become pregnant, or breastfeeding should consult their physician before using Nasomaris to weigh potential benefits against any possible risks.
How do I order Nasomaris from GNH USA?+
To order Nasomaris, submit an enquiry on the product page at gnh-usa.com, specifying the required quantity. GNH USA works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.
How does Nasomaris compare with other nasal decongestants?+
Nasomaris (xylometazoline) and oxymetazoline belong to the same imidazoline class and share a similar mechanism of vasoconstriction. Xylometazoline may have a slightly longer duration of action, while oxymetazoline is often marketed in higher‑strength formulations. Both should be limited to short‑term use to avoid rebound congestion.
How should Nasomaris be stored and handled?+
Store Nasomaris at room temperature, preferably below 25 °C. Keep the bottle tightly closed in its original packaging, protect it from moisture, direct sunlight, and extreme temperatures. Do not freeze the product, and keep it out of reach of children.
How is Nasomaris administered?+
Nasomaris is a nasal spray. The user tilts the head slightly forward, inserts the nozzle into one nostril, and gently presses the pump to deliver the recommended number of sprays. The same procedure is repeated for the other nostril if instructed by the prescriber.
What are the most serious risks associated with Nasomaris?+
Serious risks include elevated blood pressure, severe nasal irritation or ulceration, and rare allergic reactions such as rash, facial swelling, or anaphylaxis. If any of these occur, discontinue use immediately and seek medical attention.
Who should not use Nasomaris?+
Nasomaris should be avoided in individuals with known hypersensitivity to xylometazoline or any formulation components, in children under two years of age unless directed by a physician, and in patients with uncontrolled hypertension or severe cardiovascular disease without medical supervision.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Xylometazoline Hydrochloride
Route
Nasal Use
Manufacturer
Jadran-Galenski Laboratorij D.D.
Origin
EU

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